Actively Recruiting

Phase 2
Age: 2Years - 11Years
All Genders
NCT07470879

A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis

Led by Pfizer · Updated on 2026-05-06

24

Participants Needed

9

Research Sites

429 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in pediatrics participants (≥ 2 years up to \< 12 years of age). Participants who will complete the total 52-week treatment period will have the opportunity to continue in a Long-Term Extension (LTE) Period of up to 4 years (5 years after study enrollment).

CONDITIONS

Official Title

A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis

Who Can Participate

Age: 2Years - 11Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a diagnosis of ulcerative colitis that is moderately to severely active
  • Participants may be receiving a therapeutic dose of select ulcerative colitis therapies
  • Age between 2 and 11 years
Not Eligible

You will not qualify if you...

  • Severe extensive colitis
  • Diagnosis of Crohn's disease, indeterminate colitis, or history of fistula consistent with Crohn's disease
  • Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

CHU de Québec - Université Laval

Québec, Quebec, Canada, G1V4G2

Actively Recruiting

2

Universitätsklinikum Leipzig

Leipzig, Saxony, Germany, 04103

Not Yet Recruiting

3

Universitaetsklinikum Tuebingen

Tübingen, Germany, 72076

Not Yet Recruiting

4

Saitama Prefectural Children's Medical Center

Saitama-shi, Saitama, Japan, 330-8777

Actively Recruiting

5

Japanese Red Cross Kumamoto Hospital

Kumamoto, Japan, 861-8520

Actively Recruiting

6

Juntendo University Hospital

Tokyo, Japan, 113-8431

Actively Recruiting

7

Centrum Zdrowia MDM

Warsaw, Masovian Voivodeship, Poland, 00-189

Not Yet Recruiting

8

Medical Network Spółka z o.o. WIP Warsaw IBD Point Profesor Kierkuś

Warsaw, Masovian Voivodeship, Poland, 04-501

Actively Recruiting

9

Gyncentrum sp. z o.o. NZOZ Holsamed - oddział Libero

Katowice, Poland, 40-600

Not Yet Recruiting

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Research Team

P

Pfizer CT.gov Call Center

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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