Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT05473624

Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors

Led by Jiangsu HengRui Medicine Co., Ltd. · Updated on 2025-04-15

153

Participants Needed

20

Research Sites

227 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is designed to determine if treatment with HRS-1167 alone is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

CONDITIONS

Official Title

Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • ECOG performance status 0-1
  • Life expectancy of at least 12 weeks
  • Diagnosed with advanced solid tumors refractory to standard therapies or with no standard therapy available
  • For efficacy expansion: diagnosed with ovarian, breast, pancreatic, prostate cancer, or other cancers with HRR gene mutation
  • At least one measurable target lesion, except for maintenance therapy
  • Adequate organ and bone marrow function as required by the protocol
Not Eligible

You will not qualify if you...

  • Surgery or chemotherapy within 4 weeks before starting study treatment
  • Unable to swallow or have gastrointestinal absorption problems
  • Active hepatitis B, hepatitis C, or HIV infection
  • Untreated or uncontrolled brain metastases

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 20 locations

1

Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China, 100021

Actively Recruiting

2

Chongqing Cancer Hospital

Chongqing, Chongqing Municipality, China, 400030

Actively Recruiting

3

Guangxi Medical University Affiliated Tumor Hosipital

Nanning, Guangxi, China, 530021

Actively Recruiting

4

Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

Guangzhou, Guangzhou, China, 510120

Actively Recruiting

5

Harbin Medical University Cancer Hospital

Harbin, Heilongjiang, China, 150081

Actively Recruiting

6

Henan Cancer Hospital

Zhengzhou, Henan, China, 450008

Actively Recruiting

7

Hunan Cancer Hospital

Changsha, Hunan, China, 410013

Actively Recruiting

8

Hunan Cancer Hospital

Changsha, Hunan, China, 410013

Actively Recruiting

9

The First Affiliated Hospital with Nanjing Medical University

Nanjing, Jiangsu, China, 210029

Actively Recruiting

10

The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China, 330209

Actively Recruiting

11

The First Hospital of Jilin University

Changchun, Jilin, China, 130021

Actively Recruiting

12

The First Hospital of China Medical University

Shenyang, Liaoning, China, 110001

Actively Recruiting

13

Liaoning Cancer Hospital

Shenyang, Liaoning, China, 110042

Actively Recruiting

14

Qilu Hospital of Shandong University

Jinan, Shangdong, China, 250062

Actively Recruiting

15

Shandong Cancer Hospital

Jinan, Shangdong, China, 250117

Actively Recruiting

16

Second Hospital of Shanxi Medical University

Taiyuan, Shanxi, China, 030001

Actively Recruiting

17

Shanxi Provincial Cancer Hospital

Taiyuan, Shanxi, China, 030013

Actively Recruiting

18

The Affiliated Hospital of Southwest Medical University

Luzhou, Sichuan, China, 646099

Actively Recruiting

19

Tianjin Medical University Cancer Institute & Hospital

Tianjin, Tianjin Municipality, China, 300060

Actively Recruiting

20

Zhejiang Cancer Hospital

Hangzhou, Zhengjiang, China, 310022

Actively Recruiting

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Research Team

Q

Quanren Wang, M.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors | DecenTrialz