Actively Recruiting
Study of the Impact of Cataract Surgery on the Corneal Epithelium and Ocular Surface of Diabetic Patients
Led by University Hospital, Strasbourg, France · Updated on 2024-10-15
150
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Diabetes is one of the most common fatal metabolic diseases in the world. Diabetes-induced ocular surface alterations are poorly understood. Indeed, it was once thought that the cornea, avascular, was immune to the effects of diabetes. A growing number of publications now demonstrate the opposite. These alterations affect up to 70% of diabetic patients at some point in the progression of their diabetes. Another common complication of diabetes is the early development of a cataract, requiring surgery. Diabetic patients are therefore more likely to require surgery at an early age than the general population. Diabetes and cataract surgery both induce corneal changes. Cataract surgery in diabetic patients is therefore at greater risk of corneal complications. Diabetes induces dysfunction of the main lacrimal gland, corneal neuropathy, meibomian dysfunction and a decrease in conjunctival mucus cells. Diabetic patients are therefore particularly at risk of exacerbation or appearance of alterations of the corneal epithelium and the ocular surface in postoperative cataract surgery. Therefore, it seems necessary to evaluate the impact of cataract surgery on the ocular surface and corneal epithelium of diabetic patients, in order to improve their management.
CONDITIONS
Official Title
Study of the Impact of Cataract Surgery on the Corneal Epithelium and Ocular Surface of Diabetic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient (≥18 years)
- Patient operated on for cataract at HUS between January 2022 and January 2024
- Patient who did not express opposition to reuse of their data for scientific research
- Patient who had measurements of eye health criteria during pre- and post-operative consultations
You will not qualify if you...
- Subject's medical file shows opposition to reuse of data for scientific research
- Prolonged use of stored eye drops
- Chronic ocular surface alteration due to conditions like shingles, herpes, Gougerot-Sjogren syndrome, or graft-versus-host disease
- Minor patient or under guardianship or curatorship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service d'Ophtalmologie - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
T
Tristan BOURCIER, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here