Impact of Mother-of-pearl Supplement on Preventing Post-menopausal Osteoporosis in Women Aged 50 to 65

What this Trial Is About

Post-menopausal osteoporosis is a common cause of disability and loss of independence in women aged 50 to 65. The decrease in hormone replacement therapy use has increased the risk of osteoporotic fractures in women before age 70, highlighting the need for effective prevention methods. This study investigates whether mother-of-pearl supplementation can help limit bone loss in postmenopausal women at risk of osteoporosis. Participants are randomly assigned to one of two groups one receiving mother-of-pearl capsules 800 mg daily, providing 320 mg calcium plus monthly vitamin D, and the other receiving calcium carbonate capsules 800 mg daily, equivalent to 320 mg calcium plus monthly vitamin D as a control. The study is double-blind and compares the effects of these supplementations over 12 months. Women in the study will undergo assessments of bone loss at the lumbar spine and femur, bone remodeling measurements, and monitoring of tolerance to mother-of-pearl supplementation. These evaluations occur from the start of the study through 12 months. The study follows participants for safety and effectiveness over this period, with the goal of understanding the impact on bone health.

Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis