Actively Recruiting

Phase Not Applicable
Age: 50Years - 65Years
FEMALE
NCT05571514

Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis

Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2025-06-19

200

Participants Needed

7

Research Sites

285 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de Saint Etienne

Lead Sponsor

M

Ministry of Health, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality. Given potential side effects, hormone replacement therapy is no longer recommended for menopausal women with risk of becoming osteoporotic. The very significant decrease in the use of these treatments is suspected of contributing to a resurgence in the incidence of osteoporotic fractures, particularly in women before the age of 70. There is a need for prevention of osteoporosis.

CONDITIONS

Official Title

Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis

Who Can Participate

Age: 50Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Post-menopausal women aged 50 to 65 years at risk of becoming osteoporotic
  • Bone density T-score between -1 and -3
  • No history of fragility fractures
Not Eligible

You will not qualify if you...

  • Absence of parathyroid glands affecting phosphate and calcium regulation
  • Presence of kidney stones
  • Current treatment affecting bone metabolism (corticosteroids, menopausal hormone therapy, anti-estrogen treatment, uncontrolled thyroid disorders)
  • Bone diseases such as Paget's disease or osteomalacia
  • Chronic alcoholism

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Hôpital Gabriel Montpied

Clermont-Ferrand, France

Not Yet Recruiting

2

Clinique Universitaire de Rhumatologie

Grenoble, France

Not Yet Recruiting

3

CH Emile Roux

Le Puy-en-Velay, France

Not Yet Recruiting

4

Hôpital Edouard Herriot

Lyon, France

Not Yet Recruiting

5

APHP - Hôpital Cochin

Paris, France, 75014

Not Yet Recruiting

6

CH Roanne

Roanne, France

Not Yet Recruiting

7

CHU Saint-Etienne

Saint-Etienne, France

Actively Recruiting

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Research Team

A

Adamah AMOUZOUGAN, MD

CONTACT

F

Florence RANCON, CRA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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