Actively Recruiting
Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion
Led by Qifu Li · Updated on 2026-05-01
521
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the incidence of adrenal insufficiency after surgery in Primary aldosteronism (PA) patients concurrent with or without autonomous cortisol secretion (ACS). To assess the recovery time of postoperative adrenal insufficiency in patients. And to explore the clinical characteristics and predictive indicators of patients requiring postoperative hormone replacement therapy.
CONDITIONS
Official Title
Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of primary aldosteronism or autonomous cortisol secretion
- Completion of unilateral adrenal surgery
- Voluntary participation with informed consent
You will not qualify if you...
- Typical clinical signs of Cushing's syndrome
- Suspected bilateral cortisol over-secretion such as PBMAH or PPNAD
- Severe surgical complications or unstable postoperative condition not related to adrenal insufficiency
- History of allergy to ACTH
- Requirement of long-term hormone therapy for other diseases
- Severe liver or kidney dysfunction (ALT three times above normal; dialysis or eGFR less than 30 ml/min/m2)
- History of contralateral adrenal surgery
- Poor compliance preventing completion of the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Chongqing, Chongqing Municipality, China, 400016
Actively Recruiting
Research Team
L
Li Qifu, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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