Actively Recruiting

Phase 1
Age: 18Years - 75Years
All Genders
NCT06826313

A Study of Intravenous VRT106 for Locally Advanced or Metastatic Solid Tumors

Led by Guangzhou Virotech Pharmaceutical Co., Ltd. · Updated on 2025-07-18

12

Participants Needed

1

Research Sites

101 weeks

Total Duration

On this page

Sponsors

G

Guangzhou Virotech Pharmaceutical Co., Ltd.

Lead Sponsor

T

Third Affiliated Hospital, Sun Yat-Sen University

Collaborating Sponsor

AI-Summary

What this Trial Is About

A Phase I Study of the Safety and Tolerability of VRT106 Administered Intravenously for Treatment of Patients With Locally Advanced or MetastaticSolid Tumors

CONDITIONS

Official Title

A Study of Intravenous VRT106 for Locally Advanced or Metastatic Solid Tumors

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntarily agree to participate, understand the study, and can complete all procedures
  • Male or female aged 18 to 75 years at the time of informed consent
  • Histologically or cytologically confirmed intolerant or refractory to standard systemic treatment
  • Have at least one measurable lesion
  • ECOG performance status of 0 to 2 within 28 days prior to first dose
  • Expected survival time of at least 12 weeks
  • Sufficient organ function
  • Female patients of childbearing potential with a negative pregnancy test within 7 days prior to first dose
  • Agree to use effective birth control from informed consent to 90 days after last dose (for males and females of childbearing potential)
Not Eligible

You will not qualify if you...

  • Received any antitumor therapy within 4 weeks prior to first dose
  • Previously treated with oncolytic virus or other gene therapy
  • Received other investigational drugs or devices within 4 weeks prior to first dose
  • Known allergy to any components of the investigational medicinal product
  • Women who are breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Third Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510000

Actively Recruiting

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Research Team

T

Third Affiliated Hospital, Sun Yat-sen University

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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A Study of Intravenous VRT106 for Locally Advanced or Metastatic Solid Tumors | DecenTrialz