Actively Recruiting
A Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy Participants
Led by AstraZeneca · Updated on 2026-05-12
40
Participants Needed
2
Research Sites
22 weeks
Total Duration
On this page
Sponsors
A
AstraZeneca
Lead Sponsor
P
Parexel
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study has 2 groups, one each focusing on co-administration of elecoglipron and atorvastatin or rosuvastatin to assess the pharmacokinetics (PK) of atorvastatin in healthy participants.
CONDITIONS
Official Title
A Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy Participants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All females must have a negative pregnancy test at screening and admission
- Females of childbearing potential must not be breastfeeding and must use effective contraception if sexually active
- Females not of childbearing potential must be postmenopausal or surgically sterilized by hysterectomy, bilateral oophorectomy, or bilateral salpingectomy
- Sexually active fertile male participants with partners of childbearing potential must use contraception
You will not qualify if you...
- History of any clinically important disease or disorder
- Cardiovascular diseases, neuromuscular or neurogenic disease, type 1 or type 2 diabetes mellitus, HIV infection, or uncontrolled thyroid disease
- History of acute pancreatitis or gastrointestinal conditions affecting drug absorption or metabolism
- Clinically significant inflammatory bowel disease, gastroparesis, severe disease, or surgery affecting the upper gastrointestinal tract
- Any important illness, surgery, or trauma within 4 weeks before study treatment
- Clinically important abnormalities in lab tests or vital signs
- Abnormalities in resting 12-lead electrocardiogram
- History of severe allergy or ongoing allergy to drugs similar to elecoglipron or paracetamol
- Previously received elecoglipron in last 6 months or statin treatment within 4 weeks prior to study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Research Site
Glendale, California, United States, 91206
Not Yet Recruiting
2
Research Site
Brooklyn, Maryland, United States, 21225
Actively Recruiting
Research Team
A
AstraZeneca Clinical Study Information Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
11
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