Actively Recruiting

Age: 18Years +
All Genders
NCT06780150

A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)

Led by Hoffmann-La Roche · Updated on 2026-04-27

842

Participants Needed

84

Research Sites

183 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main purpose of the study is to evaluate participant satisfaction after administration of ocrelizumab subcutaneous (SC) after 12 months using the therapy administration satisfaction questionnaire subcutaneous (TASQ-SC).

CONDITIONS

Official Title

A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of MS
  • RMS and PPMS participants diagnosed according to the McDonald criteria of 2017
  • First treatment during the course of MS therapy with ocrelizumab SC according to the local prescribing information, regardless of the reason for starting treatment with ocrelizumab
Not Eligible

You will not qualify if you...

  • Participation in interventional studies investigating DMTs for MS
  • Prior or simultaneous participation in CONFIDENCE or MoOzaRt (ISRCTN55332718) non interventional study (NIS) at the same study site
  • Prior treatment with rituximab (MabThera�) or ublituximab (Briumvi�)
  • Severe psychiatric disability
  • Pregnant women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 84 locations

1

Uniklinik RWTH Aachen

Aachen, Germany, 52074

Actively Recruiting

2

Gesundheitszentrum St. Marien GmbH

Amberg, Germany, 92224

Actively Recruiting

3

Neuropraxis im Stadtpalais Dres. Ulzheimer/Herröder/Wessig GbR

Aschaffenburg, Germany, 63739

Actively Recruiting

4

Neurologie Bad Soden

Bad Soden, Germany, 65812

Actively Recruiting

5

Neurologische Praxis - Kallmann Neurologie - mszb

Bamberg, Germany, 96052

Actively Recruiting

6

Neurologisches Facharztzentrum Berlin am Sankt Gertrauden-Krankenhaus

Berlin, Germany, 10713

Actively Recruiting

7

NEUROZENTRUM tempelhof.berlin

Berlin, Germany, 12099

Actively Recruiting

8

Praxis Dr. Said Masri

Berlin, Germany, 12099

Actively Recruiting

9

Jüdisches Krankenhaus Berlin

Berlin, Germany, 13347

Actively Recruiting

10

NeuroZentrum Zehlendorf Dr. Ringel und Dr. Scherer

Berlin, Germany, 14169

Actively Recruiting

11

Neurologisches Zentrum für Bewegungsstörungen und Diagnostik

Berlin, Germany, 14195

Actively Recruiting

12

St. Josef-Hospital

Bochum, Germany, 44791

Actively Recruiting

13

Dres. Lippert/Kausch

Bogen, Germany, 94327

Actively Recruiting

14

Krankenhaus Buchholz Abt. Neurologie

Buchholz, Germany, 21244

Actively Recruiting

15

Allgemeines Krankenhaus Celle / Klinik für Neurologie

Celle, Germany, 29223

Actively Recruiting

16

Neuropraxis Celle: Praxis für Neurologie & Psychatrie

Celle, Germany, 29223

Actively Recruiting

17

Praxisgemeinschaft Dres. Sylke Domke und Vasil Gjaurov

Chemnitz, Germany, 09117

Actively Recruiting

18

NeuroMed Campus Neurologische Gemeinschaftspraxis am St. Elisabeth Krankenhaus

Cologne, Germany, 50935

Actively Recruiting

19

Gemeinschaftspraxis Dr. med. Josef Leclaire und Dr. med. Thomas Rotermund

Dortmund, Germany, 44137

Withdrawn

20

Gemeinschaftspraxis für Neurologie

Düsseldorf, Germany, 40211

Actively Recruiting

21

Universitätsklinikum Düsseldorf

Düsseldorf, Germany, 40225

Actively Recruiting

22

Nervenarztpraxis Gerresheim

Düsseldorf, Germany, 40625

Actively Recruiting

23

Gemeinschaftspraxis für Neurologie und Psychiatrie, Psychotherapie

Eltville, Germany, 65343

Actively Recruiting

24

NeuroCentrum Odenwald

Erbach/Odenwald, Germany, 64711

Actively Recruiting

25

Universitätsklinikum Erlangen, Neurologische Klinik

Erlangen, Germany, 91054

Actively Recruiting

26

Zentrum für ambulante Neurologie / Praxis Knorn Landefeld Friedrich

Essen, Germany, 45138

Actively Recruiting

27

Praxis Nervenstark

Essen, Germany, 45257

Actively Recruiting

28

Praxis für Neurologie, Nervenheilkunde & Neurochirurgie

Forchheim, Germany, 91301

Withdrawn

29

Varisano Klinikum Frankfurt Höchst GmbH

Frankfurt, Germany, 65929

Actively Recruiting

30

Universitätsklinikum Freiburg, Klinik für Neurologie und Neurophysiologie

Freiburg im Breisgau, Germany, 79106

Actively Recruiting

31

Praxis im Bahnhof

Füssen, Germany, 87629

Actively Recruiting

32

Universitätsklinikum Gießen und Marburg GmbH

Giessen, Germany, 35392

Actively Recruiting

33

Neurologie & Psychiatrie Gladenbach - MS-Zentrum

Gladenbach, Germany, 35075

Actively Recruiting

34

MVZ Bezirkskliniken Schwaben, Standort Günzburg

Günzburg, Germany, 89312

Actively Recruiting

35

Krankenhaus Martha-Maria Halle-Doelau

Halle, Germany, 06120

Actively Recruiting

36

Universiätsklinikum Hamburg-Eppendorf

Hamburg, Germany, 20246

Actively Recruiting

37

Neurologische Praxis Eppendorf

Hamburg, Germany, 20249

Actively Recruiting

38

Neurologische Praxis

Hanover, Germany, 30171

Actively Recruiting

39

Oberhavel Kliniken GmbH, Klinik Hennigsdorf, Neurologie

Hennigsdorf, Germany, 16761

Actively Recruiting

40

Praxis Dr. Hospely

Herford, Germany, 32052

Actively Recruiting

41

Haus- und Facharztzentrum Laucherttal / Alb

Hettingen, Germany, 72513

Actively Recruiting

42

Klinikum Ibbenbüren gmbH

Ibbenbueren, Germany, 49477

Actively Recruiting

43

Augustahospital Anholt;Neurologie

Isselburg, Germany, 46419

Actively Recruiting

44

Universitätsklinikum Jena, Klinik für Neurologie

Jena, Germany, 07747

Actively Recruiting

45

Arztpraxis Dr. med. Torsten Sühnel

Leipzig, Germany, 04299

Actively Recruiting

46

Neurologische Praxis Dr. Ehrlich

Leipzig, Germany, 04315

Actively Recruiting

47

Neurologie im Ulrichshaus Magdeburg

Magdeburg, Germany, 39104

Actively Recruiting

48

Universitätsklinikum Magdeburg

Magdeburg, Germany, 39120

Actively Recruiting

49

Neuroplus Dres. Lennart Thilmann/ Patrick Thilmann

Mannheim, Germany, 68163

Actively Recruiting

50

Universitätsklinikum Mannheim

Mannheim, Germany, 68167

Actively Recruiting

51

Universitätsklinikum Giessen und Marburg

Marburg, Germany, 35043

Actively Recruiting

52

Praxis Dr. Leussink

Meerbusch, Germany, 40667

Actively Recruiting

53

Neurologie am Preußenmuseum

Minden, Germany, 32423

Actively Recruiting

54

Neurologie München Nord

München, Germany, 80939

Actively Recruiting

55

Praxis für Neurologie und Psychiatrie am Prinzregentenplatz

München, Germany, 81675

Actively Recruiting

56

Neurologisch-psychiatrische Praxis im A4

Neu-Ulm, Germany, 89231

Actively Recruiting

57

Praxis Dr. med. Bergmann

Neuburg am Inn, Germany, 86633

Actively Recruiting

58

Gemeinschaftspraxis Uhlig und Windsheimer

Nuremberg, Germany, 90419

Actively Recruiting

59

Neurologie Nürnberg-Eibach

Nuremberg, Germany, 90451

Actively Recruiting

60

Neurologie an der Hase

Osnabrück, Germany, 49074

Actively Recruiting

61

Dres. Beckmann / Schlüter

Öhringen, Germany, 74613

Actively Recruiting

62

Facharztpraxis für Neurologie und Psychiatrie Dres Mattes/Stockert

Pforzheim, Germany, 75172

Actively Recruiting

63

Neurologisches Studienzentrum Artland

Quakenbrück, Germany, 49610

Actively Recruiting

64

Gemeinschaftspraxis für Neurologie

Regensburg, Germany, 93059

Actively Recruiting

65

Praxis Dr. Stienker-Fisse

Remscheid, Germany, 42853

Actively Recruiting

66

ZNS Südpfalz

Rülzheim, Germany, 76761

Actively Recruiting

67

Neurologische Praxis Dr. Wagner

Schwetzingen, Germany, 68723

Actively Recruiting

68

Gemeinschaftspraxis für Neurologie, Psychiatrie und Psychotherapie

Siegen, Germany, 57072

Actively Recruiting

69

Praxis für Neurologie und Psychiatrie

Siegen, Germany, 57076

Actively Recruiting

70

EMSA - Zentrum für Neurologie?/?Psychiatrie?/?Neuroradiologie

Singen, Germany, 78224

Actively Recruiting

71

Praxis Dr. med. Max Deist und Michael Ernst ?Sinsheim

Sinsheim, Germany, 74889

Actively Recruiting

72

Gemeinschaftspraxis Dr. Wolfram von Pannwitz, MBA & Dr. med. Marie Perle Brinckmann

Steglitz, Germany, 12163

Actively Recruiting

73

Praxis Dr. med. Andreas Kowalik, Arzt für Neurologie und Psychiatrie

Stuttgart, Germany, 70174

Actively Recruiting

74

Neuropraxis Sotiriadis

Stuttgart, Germany, 70176

Actively Recruiting

75

Neurozentrum Stuttgart Mitte Sophienstraße

Stuttgart, Germany, 70178

Actively Recruiting

76

Sauerlandklinik Hachen

Sundern, Germany, 59846

Actively Recruiting

77

Universitätsklinikum Tübingen, Zentrum für Neurologie

Tübingen, Germany, 72076

Actively Recruiting

78

Nervenfachaerztliche Gemeinschaftspraxis Ulm

Ulm, Germany, 89078

Actively Recruiting

79

Neuropraxis München Süd

Unterhaching, Germany, 82008

Actively Recruiting

80

Praxis für Neurologie, Psychiatrie und Epileptologie

Weil der Stadt, Germany, 71263

Actively Recruiting

81

Praxis Dr. Michaela Krause

Wolfratshausen, Germany, 82515

Actively Recruiting

82

Heinrich-Braun-Krankenhaus Städtisches Klinikum

Zwickau, Germany, 08060

Actively Recruiting

83

Inselspital-Universitaetsspital Bern

Bern, Switzerland, 3010

Actively Recruiting

84

Bellevue Medical Grop AG

Zurich, Switzerland, 8001

Actively Recruiting

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Research Team

R

Reference Study ID Number: ML45551 https://forpatients.roche.com/

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS) | DecenTrialz