Actively Recruiting
A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years
Led by AstraZeneca · Updated on 2026-04-23
64
Participants Needed
2
Research Sites
13 weeks
Total Duration
On this page
Sponsors
A
AstraZeneca
Lead Sponsor
P
Parexel
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to assess the pharmacokinetics (PK), safety and tolerability of different oral formulations of AZD5004, and to evaluate the effect of food on these formulations in healthy participants.
CONDITIONS
Official Title
A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Suitable veins for cannulation or repeated venipuncture
- Negative pregnancy test at screening and on admission for all females
- Female participants of childbearing potential must not be lactating and agree to use effective contraception if sexually active
- Female participants of non-childbearing potential must be confirmed at screening
- Sexually active fertile male participants must use contraception and ensure partners use additional contraception throughout the study
- Body Mass Index (BMI) between 23 and 35 kg/m2 inclusive at screening
- Weight of at least 60 kg
You will not qualify if you...
- History of any clinically important disease or disorder that could risk safety or affect study participation
- Any clinically significant illness, medical or surgical procedure, or trauma
- Special dietary requirements preventing following a uniform diet
- Positive for anti-hepatitis B core antibody or anti-hepatitis C virus antibody
- Current or planned participation in a weight loss program during the study
- Abnormal vital signs after 10 minutes of supine rest at screening or admission
- Positive screen for drugs of abuse, alcohol, or nicotine
- Laboratory results with clinically important abnormalities or specified deviations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Research Site
Glendale, California, United States, 91206
Actively Recruiting
2
Research Site
Baltimore, Maryland, United States, 21225
Actively Recruiting
Research Team
A
AstraZeneca Clinical Study Information Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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