Actively Recruiting
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
Led by University of Colorado, Denver · Updated on 2026-02-20
80
Participants Needed
1
Research Sites
154 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).
CONDITIONS
Official Title
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged 18-65
- Ability to sign informed consent
- Ability to follow written and verbal instructions
- For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments
You will not qualify if you...
- Current uncontrolled and/or clinically significant medical condition
- Abnormal ear anatomy or active ear infection
- Electronic medical implants, such as pacemakers, cochlear prosthesis, neuro-stimulators
- Uncorrected visual impairments that would interfere with task performance
- Other significant diseases or disorders that might impair study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Clinical Translational Research Center at CU Anschutz
Aurora, Colorado, United States, 80045
Actively Recruiting
Research Team
E
Elise R Carter
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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