Pilot Study of Peripheral Cryoneurolysis Device for Treating Adults with Medication-Resistant Chronic Migraine

What this Trial Is About

Researchers are evaluating a freezing technique called cryoneurolysis to see if it helps relieve pain in adults with chronic migraine, a condition causing moderate to severe headaches. The study aims to measure headache relief after treatment and gather other important participant information to assess the potential of this technique as a treatment option. This is an open label pilot study conducted by St. Olavs Hospital focusing on medically resistant chronic migraine. Participants will use a headache diary for at least 4 weeks before receiving cryoneurolysis treatment. After the initial treatment, those with recurring headaches may receive further treatment as needed for up to two years. The study involves administering the cryoneurolysis device to target peripheral nerves to reduce migraine symptoms. During the study, participants will record headache severity and frequency in their diaries both before and after treatment. Researchers will monitor headache days with moderate and severe intensity, migraine days, medication use, and any adverse events over an 8-week period post-intervention. The total participation may last up to two years with ongoing follow-up for safety and treatment effectiveness.

A Study Investigating Peripheral Cryoneurolysis in Adults With Chronic Migraine