Actively Recruiting
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
Led by Janssen Research & Development, LLC · Updated on 2026-05-08
157
Participants Needed
37
Research Sites
148 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate how well JNJ-79635322 works (efficacy) in participants with Relapsed or Refractory Multiple Myeloma (RRMM; a cancer that forms in a type of white blood cells called a plasma cell. Cancer is called relapsed if it comes back after treatment and is called 'refractory' if does not respond to treatment) who have received at least 3 prior lines of therapy.
CONDITIONS
Official Title
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Documented diagnosis of multiple myeloma according to international myeloma working group criteria
- Measurable disease at screening as confirmed by central laboratory
- Received at least 3 prior antimyeloma treatments including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 monoclonal antibody
- Evidence of progressive disease or no response to last therapy based on investigator assessment
- Stopped any other anticancer treatments or investigational agents before starting this study
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2 at screening and before treatment start
You will not qualify if you...
- Known allergies or intolerance to ingredients in JNJ-79635322
- Major surgery within 2 weeks before first dose or planned major surgery during treatment phase
- Known active or prior central nervous system involvement or signs of meningeal involvement of multiple myeloma
- Diagnosis of leptomeningeal disease
- Prior or current second cancer that could affect study safety or treatment efficacy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 37 locations
1
O Neal Comprehensive Cancer Center at UAB
Birmingham, Alabama, United States, 35294
Actively Recruiting
2
Banner MD Anderson Cancer Center
Gilbert, Arizona, United States, 85234
Actively Recruiting
3
City of Hope
Duarte, California, United States, 91010
Actively Recruiting
4
City of Hope Orange County Lennar Foundation Cancer Center
Irvine, California, United States, 92618
Actively Recruiting
5
Cancer and Blood Specialty Clinic
Los Alamitos, California, United States, 90720
Actively Recruiting
6
University of California San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
7
Rocky Mountain Cancer Centers
Aurora, Colorado, United States, 80012
Actively Recruiting
8
Colorado Blood Cancer Institute
Denver, Colorado, United States, 80218
Actively Recruiting
9
Cancer Specialists of North Florida
Jacksonville, Florida, United States, 32256
Actively Recruiting
10
Emory University
Atlanta, Georgia, United States, 30322
Actively Recruiting
11
Northside Hospital Cancer Institute
Atlanta, Georgia, United States, 30342
Actively Recruiting
12
Cancer Care Specialists of Central Illinois
O'Fallon, Illinois, United States, 62269
Actively Recruiting
13
University of Iowa
Iowa City, Iowa, United States, 52242
Actively Recruiting
14
Mission Cancer Blood
Waukee, Iowa, United States, 50263
Actively Recruiting
15
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
16
Rutgers Cancer Institute
New Brunswick, New Jersey, United States, 08901
Actively Recruiting
17
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Actively Recruiting
18
Cleveland Clinic Foundtation
Cleveland, Ohio, United States, 44195
Actively Recruiting
19
Oncology Associates of Oregon PC Willamette Valley Cancer Institute
Eugene, Oregon, United States, 97401
Actively Recruiting
20
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
21
SCRI Oncology Partners
Nashville, Tennessee, United States, 37203
Actively Recruiting
22
Tennessee Oncology, PLLC
Nashville, Tennessee, United States, 37203
Actively Recruiting
23
Texas Oncology
Austin, Texas, United States, 78705
Actively Recruiting
24
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
25
Oncology Consultants Texas
Houston, Texas, United States, 77030
Actively Recruiting
26
Texas Oncology - Northeast
Tyler, Texas, United States, 75702
Actively Recruiting
27
Virginia Cancer Specialists
Fairfax, Virginia, United States, 22031
Actively Recruiting
28
Virginia Oncology Associates
Norfolk, Virginia, United States, 23502
Actively Recruiting
29
NorthWest Medical Specialties, PLLC
Tacoma, Washington, United States, 98405
Actively Recruiting
30
Ha'Emek Medical Center
Afula, Israel, 1834111
Actively Recruiting
31
Samson Assuta Ashdod University Hospital
Ashdod, Israel, 7747629
Actively Recruiting
32
Hillel Yaffe Medical Center
Hadera, Israel, 3820302
Actively Recruiting
33
Hadassah Medical Center
Jerusalem, Israel, 9112000
Actively Recruiting
34
Rabin Medical Center
Petah Tikva, Israel, 4941492
Actively Recruiting
35
Tel Aviv Sourasky Medical Center
Tel Aviv, Israel, 6423906
Actively Recruiting
36
National Hospital Organization Shibukawa Medical Center
Gunma, Japan, 377-0280
Actively Recruiting
37
National Hospital Organization Okayama Medical Center
Okayama, Japan, 701-1192
Actively Recruiting
Research Team
S
Study Contact
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here