Actively Recruiting

Age: 18Years +
All Genders
NCT06246123

A Study of Jyseleca Tablet (Filgotinib Maleate) in Korean Participants

Led by Eisai Korea Inc. · Updated on 2026-04-07

2040

Participants Needed

64

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to collect and evaluate the following information in relation to the safety and the efficacy of Jyseleca tablet (Filgotinib Maleate) 100 milligram (mg) and 200 mg in this post marketing setting: (1) Serious adverse events and adverse drug reactions (2) Unexpected adverse events and adverse drug reactions not reflected in precautions for use (3) Known adverse drug reactions (4) Non-serious adverse events and adverse drug reactions (5) Other safety and effectiveness related information will be evaluated in accordance with the permitted articles under the actual conditions of use in Korea.

CONDITIONS

Official Title

A Study of Jyseleca Tablet (Filgotinib Maleate) in Korean Participants

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals currently taking Jyseleca tablet according to the Korean approved therapeutic indications.
  • Participants over 65 years of age, or with high cardiovascular risk, or with malignancy can be included if they meet label criteria.
  • Adults with moderately to severely active rheumatoid arthritis who have not responded well or are intolerant to one or more disease-modifying anti-rheumatic drugs.
  • Jyseleca may be used alone or with methotrexate in rheumatoid arthritis, but not with biological DMARDs or other JAK inhibitors.
  • Adults with moderately to severely active ulcerative colitis who have inadequate response, lost response, or intolerance to conventional or biological therapies.
  • Investigator must refer to local label and contraindications in Korea for inclusion.
Not Eligible

You will not qualify if you...

  • Individuals with contraindications to Jyseleca tablet as per Korean label and investigator judgment.
  • Participants with hypersensitivity to Jyseleca ingredients.
  • Those with active infections, including serious or local infections.
  • Participants with active tuberculosis.
  • Individuals with severe liver disorder or end-stage renal disorder.
  • Those with absolute neutrophil count less than 1x10^9 cells/L.
  • Those with absolute lymphocyte count less than 0.5x10^9 cells/L.
  • Participants with hemoglobin less than 8 g/dL.
  • Pregnant, potentially pregnant, or lactating women.
  • Individuals with genetic disorders like galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption.
  • Participants enrolled in other clinical studies using Filgotinib.
  • Individuals considered unsuitable by investigator judgment.
  • Investigator should refer to local label and contraindications in Korea for exclusion.

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 64 locations

1

Soonchunhyang University Cheonan Hospital

Cheonan, Chungcheongnam-do, South Korea

Actively Recruiting

2

Kangwon National University Hospital

Chuncheon, Gangwon-do, South Korea

Actively Recruiting

3

Wonju Severance Christian Hospital

Wŏnju, Gangwon-do, South Korea

Actively Recruiting

4

Korea University Ansan Hospital

Ansan, Gyeonggi-do, South Korea

Actively Recruiting

5

The Catholic University of Korea Bucheon St. Mary's Hospital

Bucheon-si, Gyeonggi-do, South Korea

Actively Recruiting

6

Inje University Ilsan Paik Hospital

Goyang-si, Gyeonggi-do, South Korea

Actively Recruiting

7

Chung-Ang University Gwangmyeong Hospital

Gwangmyeong, Gyeonggi-do, South Korea

Actively Recruiting

8

CHA Bundang Medical Center

Seongnam-si, Gyeonggi-do, South Korea

Actively Recruiting

9

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea

Actively Recruiting

10

Ajou University Medical Center

Suwon, Gyeonggi-do, South Korea

Actively Recruiting

11

The Catholic University of Korea St. Vincent's Hospital

Suwon, Gyeonggi-do, South Korea

Actively Recruiting

12

Nowon Eulji Hospital

Uijeongbu-si, Gyeonggi-do, South Korea

Actively Recruiting

13

Uijeongbu Eulji Medical Center

Uijeongbu-si, Gyeonggi-do, South Korea

Actively Recruiting

14

Yongin Severance Hospital

Yongin, Gyeonggi-do, South Korea

Actively Recruiting

15

Changwon fatima hospital

Changwon, Gyeongsangnam-do, South Korea

Withdrawn

16

Changwon Gyeongsang National University Hospital

Changwon, Gyeongsangnam-do, South Korea

Actively Recruiting

17

Gyeongsang National University Hospital

Jinju, Gyeongsangnam-do, South Korea

Actively Recruiting

18

Pusan National University Yangsan Hospital

Yangsan, Gyeongsangnam-do, South Korea

Actively Recruiting

19

Jeonbuk National University Hospital

Jeonju, Jeollabuk-do, South Korea

Actively Recruiting

20

Jeonbuk National University Hospital

Jeonju, Jeollabuk-do, South Korea

Withdrawn

21

Chongbuk National University Hospital

Cheongju-si, North Chungcheong, South Korea

Actively Recruiting

22

Dong-A University Hospital

Busan, South Korea

Actively Recruiting

23

Haeundae Bumin Hospital

Busan, South Korea

Actively Recruiting

24

Inje University Haeundae Paik Hospital

Busan, South Korea

Actively Recruiting

25

Inje University Pusan Paik Hospital

Busan, South Korea

Actively Recruiting

26

Kosin University Gospel Hospital

Busan, South Korea

Actively Recruiting

27

Daegu Fatima Hospital

Daegu, South Korea

Actively Recruiting

28

Daegu Koo Hospital

Daegu, South Korea

Actively Recruiting

29

Deagu Catholic University Medical Center

Daegu, South Korea

Actively Recruiting

30

Keimyung University Dongsan Hospital

Daegu, South Korea

Withdrawn

31

Keimyung University Dongsan Hospital

Daegu, South Korea

Actively Recruiting

32

Kyungpook National University Chilgok Hospital

Daegu, South Korea

Actively Recruiting

33

Kyungpook National University Hospital

Daegu, South Korea

Actively Recruiting

34

Yeungnam University Medical Center

Daegu, South Korea

Actively Recruiting

35

Yeungnam University Medical Center

Daegu, South Korea

Withdrawn

36

Catholic University of Korea, Daejeon ST. Mary's Hospital

Daejeon, South Korea

Actively Recruiting

37

Chungnam National University Hospital

Daejeon, South Korea

Actively Recruiting

38

Eulji University Hospital Daejeon

Daejeon, South Korea

Actively Recruiting

39

Konyang University Hospital

Daejeon, South Korea

Actively Recruiting

40

Chosun University Hospital

Gwangju, South Korea

Actively Recruiting

41

Jeonnam National University Hospital

Gwangju, South Korea

Actively Recruiting

42

Catholic Kwandong University International St. Mary's Hospital

Incheon, South Korea

Actively Recruiting

43

Gachon University Gil Medical Center

Incheon, South Korea

Actively Recruiting

44

Jeju National University Hospital

Jeju City, South Korea

Actively Recruiting

45

Sejong Chungnam National University Hospital

Sejong, South Korea

Actively Recruiting

46

Asan Medical Center

Seoul, South Korea

Actively Recruiting

47

Catholic university of korea seoul st. mary's hospital

Seoul, South Korea

Actively Recruiting

48

Catholic University of Korea, Yeouido ST. Mary�s Hospital.

Seoul, South Korea

Actively Recruiting

49

Chung-Ang University Hospital

Seoul, South Korea

Actively Recruiting

50

Gangnam Severance Hospital

Seoul, South Korea

Actively Recruiting

51

Hanyang University Medical Center

Seoul, South Korea

Actively Recruiting

52

HoYounKim's Clinic

Seoul, South Korea

Actively Recruiting

53

Kangbuk Samsung Hospital

Seoul, South Korea

Actively Recruiting

54

Konkuk University Medical Center

Seoul, South Korea

Actively Recruiting

55

Konkuk University Medical Center

Seoul, South Korea

Withdrawn

56

Korea University Guro Hospital

Seoul, South Korea

Terminated

57

Kyung Hee University Hospital At Gangdong

Seoul, South Korea

Actively Recruiting

58

Kyung Hee University Hospital

Seoul, South Korea

Actively Recruiting

59

Samsung Medical Center

Seoul, South Korea

Actively Recruiting

60

Seoul National University Hospital

Seoul, South Korea

Actively Recruiting

61

Seoul St. Mary's Hospital

Seoul, South Korea

Actively Recruiting

62

Severance Hospital

Seoul, South Korea

Actively Recruiting

63

SNU Boramae Medical Center

Seoul, South Korea

Actively Recruiting

64

Soonchunhyang University Hospital Seoul

Seoul, South Korea

Actively Recruiting

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Research Team

S

Serena SoYoun Kwon

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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