Actively Recruiting
Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma
Led by Kite, A Gilead Company · Updated on 2026-04-24
247
Participants Needed
18
Research Sites
431 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical study is to learn more about the safety and effectiveness of the study drugs, KITE-363 and KITE-753, in participants with relapsed and/or refractory B-cell lymphoma.
CONDITIONS
Official Title
Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Relapsed and/or refractory B-cell lymphoma
- At least one measurable lesion
- Adequate organ and bone marrow function
- Age 18 years or older
You will not qualify if you...
- History of chimeric antigen receptor (CAR) therapy or other genetically modified T cell therapy
- History of malignancy other than nonmelanoma skin cancer or carcinoma in situ unless disease free and without anticancer therapy for at least 3 years
- History of allogeneic stem cell transplant
- Autologous stem cell transplant within 6 weeks before planned infusion
- Uncontrolled infections or infections requiring intravenous antimicrobials
- Known infection with HIV, hepatitis B (HBsAg positive), or hepatitis C (anti-HCV positive) unless viral load undetectable
- Suspected or confirmed central nervous system lymphoma
- History or presence of central nervous system disorder
- History of significant cardiac disease within 6 months before enrollment
- Primary immunodeficiency
- History of autoimmune disease requiring systemic immunosuppression or systemic disease-modifying agents within last 90 days
- Full thickness lymphoma involvement or concern for gastric or intestinal perforation
- Pregnant or breastfeeding females of childbearing potential
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
Banner MD Anderson Cancer Center
Gilbert, Arizona, United States, 85234
Actively Recruiting
2
City of Hope (City of Hope National Medical Center, City of Hope Medical Center)
Duarte, California, United States, 91010
Actively Recruiting
3
Stanford Cancer Institute
Stanford, California, United States, 94305
Actively Recruiting
4
Northside Hospital
Atlanta, Georgia, United States, 30342
Actively Recruiting
5
Midwestern Regional Medical Center, Inc.City of Hope Chicago
Park Ridge, Illinois, United States, 60068
Actively Recruiting
6
University of MD, Greenebaum Comprehensive Cancer Center
Baltimore, Maryland, United States, 21201
Actively Recruiting
7
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
Actively Recruiting
8
Columbia University Irving Medical Center
New York, New York, United States, 10032
Actively Recruiting
9
University of Rochester Medical Center
Rochester, New York, United States, 14642
Actively Recruiting
10
The Ohio State University Wexner Medical Center - James Cancer Hospital
Columbus, Ohio, United States, 43210
Actively Recruiting
11
The University of Texas, MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
12
Virginia Oncology Associates
Norfolk, Virginia, United States, 23502
Actively Recruiting
13
Royal North Shore Hospital
St Leonards, New South Wales, Australia, 2065
Actively Recruiting
14
Concord Repatriation General Hospital
Sydney, New South Wales, Australia, 2139
Actively Recruiting
15
Epworth Healthcare
East Melbourne, Victoria, Australia, 3002
Actively Recruiting
16
Universitatsklinikum Wurzburg
Würzburg, Germany, 97080
Actively Recruiting
17
Academisch Medisch Centrum
Amsterdam, Netherlands, 1105 AZ
Actively Recruiting
18
King's College Hospital
London, United Kingdom, SE5 9RS
Completed
Research Team
M
Medical Information
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
3
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