Actively Recruiting
A Study of LAD106 in Healthy Adult Participants
Led by Almirall, S.A. · Updated on 2026-03-13
93
Participants Needed
1
Research Sites
19 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main aim of this study is to assess the safety, tolerability, pharmacokinetics (PK), immunogenicity and pharmacodynamics (PD) of single ascending doses of LAD106 (Part A) and multiple ascending doses of LAD106 (Part B) in human healthy participants.
CONDITIONS
Official Title
A Study of LAD106 in Healthy Adult Participants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent and willing to follow the study protocol
- Healthy men or women aged 18 to 45 years inclusive
- Female participants agree to use effective contraception
- Male participants agree to use barrier protection during sexual relations with women of child-bearing potential or lactating women
- Body mass index (BMI) between 18 and 32 kg/m2 inclusive, with a minimum bodyweight of 50 kg
- Able to communicate well in Dutch and willing to follow study restrictions
You will not qualify if you...
- Any active or chronic disease or condition that could affect the study or pose risk, as judged by the investigator
- Clinically significant abnormal laboratory test results
- Use of any medications within 14 days before dosing or less than 5 half-lives, except paracetamol up to 4 g/day
- Pregnant, breastfeeding, or planning to become pregnant during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre for Human Drug Research (CHDR) Phase 1 Unit
Leiden, Netherlands
Actively Recruiting
Research Team
B
Begoña Begoña
CONTACT
E
Estrella Estrella
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
12
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