Actively Recruiting
A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus
Led by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Updated on 2025-01-10
34
Participants Needed
1
Research Sites
246 weeks
Total Duration
On this page
Sponsors
U
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor
N
Nanjing Legend Biotech Co.
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a prospective, single-arm, open-label, dose-exploration and expansion clinical study of LCAR-AIO in adult subjects with relapsed/refractory systemic lupus erythematosus.
CONDITIONS
Official Title
A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects voluntarily participate in clinical research
- Age 18-65 years
- Diagnosed with systemic lupus erythematosus (SLE) at least 6 months before screening
- Positive antinuclear antibody, anti-dsDNA antibody, or anti-Sm antibody at screening
- Relapsed or refractory SLE condition
- Adequate organ function at screening
- Clinical laboratory values meet criteria at screening
You will not qualify if you...
- Active infections such as hepatitis and tuberculosis
- Other autoimmune diseases
- Serious underlying diseases such as tumors or uncontrolled diabetes
- Female subjects who are pregnant, breastfeeding, or planning pregnancy during the study or within 1 year after treatment
- Participation in other clinical trials within an unspecified recent period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wuhan Union Hospital
Wuhan, Hubei, China
Actively Recruiting
Research Team
Q
Qiubai Li, Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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