Actively Recruiting

Phase 2
Age: 18Years +
All Genders
Healthy Volunteers
NCT07431853

A Study to Learn About mRNA Vaccines Against Influenza in Adults

Led by Pfizer · Updated on 2026-05-06

770

Participants Needed

15

Research Sites

69 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus). This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experimental flu vaccines or one of the approved flu vaccines used for comparison. Participants will take part in this study for about 6 months, and participants will need to visit the study site at least 3 times. A blood sample will be taken at each of the 3 planned study visits and a swab from inside the nose will be taken at the first study visit.

CONDITIONS

Official Title

A Study to Learn About mRNA Vaccines Against Influenza in Adults

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy and medically stable adults determined by medical history, physical exam if needed, and investigator's judgment
Not Eligible

You will not qualify if you...

  • Tested positive for influenza within 5 months prior to first visit
  • Received any investigational or licensed influenza vaccine within 5 months prior to first visit
  • Taken antiviral treatments for influenza (e.g., Tamiflu) within 5 months prior to first visit

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 15 locations

1

AMR Clinical

Mobile, Alabama, United States, 36608

Actively Recruiting

2

Diablo Clinical Research, LLC d/b/a Flourish Research

Walnut Creek, California, United States, 94598

Actively Recruiting

3

Clinical Research Consulting, LLC

Milford, Connecticut, United States, 06460

Actively Recruiting

4

George Washington Medical Faculty Associates

Washington D.C., District of Columbia, United States, 20037

Actively Recruiting

5

Indago Research & Health Center, Inc

Hialeah, Florida, United States, 33012

Actively Recruiting

6

Palm Springs Community Health Center

Miami Lakes, Florida, United States, 33014

Actively Recruiting

7

Clinical Research Atlanta

Stockbridge, Georgia, United States, 30281

Actively Recruiting

8

East-West Medical Research Institute

Honolulu, Hawaii, United States, 96814

Actively Recruiting

9

AMR Clinical

Kansas City, Missouri, United States, 64114

Actively Recruiting

10

Rochester Clinical Research, LLC

Rochester, New York, United States, 14609

Actively Recruiting

11

DM Clinical Research - Philadelphia

Philadelphia, Pennsylvania, United States, 19107

Actively Recruiting

12

SMS Clinical Research LLC

Mesquite, Texas, United States, 75149

Actively Recruiting

13

DM Clinical Research

Tomball, Texas, United States, 77375

Actively Recruiting

14

J. Lewis Research, Inc. / Foothill Family Clinic

Salt Lake City, Utah, United States, 84109

Actively Recruiting

15

Charlottesville Medical Research Center, LLC

Charlottesville, Virginia, United States, 22911

Actively Recruiting

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Research Team

P

Pfizer CT.gov Call Center

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

7

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A Study to Learn About mRNA Vaccines Against Influenza in Adults | DecenTrialz