Actively Recruiting
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
Led by Alterome Therapeutics, Inc. · Updated on 2026-05-06
188
Participants Needed
12
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutations.
CONDITIONS
Official Title
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed solid tumor with KRAS mutation identified by certified molecular testing
- Unresectable or metastatic disease
- Progressed on, intolerant to, or declined prior standard-of-care therapy suitable for tumor type and stage
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
- Adequate organ function
You will not qualify if you...
- Prior treatment with a KRAS inhibitor (except certain exceptions per protocol)
- Known condition preventing swallowing or absorption of oral medication
- Other inclusion/exclusion criteria may apply as detailed in full protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 12 locations
1
Research Site
Orlando, Florida, United States, 32827
Actively Recruiting
2
Research Site
Boston, Massachusetts, United States, 02114
Actively Recruiting
3
Research Site
Boston, Massachusetts, United States, 02115
Actively Recruiting
4
Research Site
St Louis, Missouri, United States, 63110
Actively Recruiting
5
Research Site
New York, New York, United States, 10016
Actively Recruiting
6
Research Site
New York, New York, United States, 10032
Actively Recruiting
7
Research Site
Durham, North Carolina, United States, 27710
Actively Recruiting
8
Research Site
Nashville, Tennessee, United States, 37203
Actively Recruiting
9
Research Site
Houston, Texas, United States, 77030
Actively Recruiting
10
Research Site #2
San Antonio, Texas, United States, 78229
Actively Recruiting
11
Research Site
San Antonio, Texas, United States, 78229
Actively Recruiting
12
Research Site
Fairfax, Virginia, United States, 22031
Actively Recruiting
Research Team
A
Alterome Clinical Trial Contact Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here