Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT07290036

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Led by UCB Biopharma SRL · Updated on 2026-05-08

392

Participants Needed

52

Research Sites

144 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To demonstrate that bimekizumab administered intravenously is noninferior to subcutaneous administration.

CONDITIONS

Official Title

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 18 years or older and legally able to consent
  • Have active psoriatic arthritis or active axial spondyloarthritis suitable for bimekizumab treatment
  • Weigh between 45 and 100 kg if female, or between 50 and 100 kg if male
  • Be biologic disease-modifying anti-rheumatic drug (bDMARD)-nafve or have stopped bDMARDs at least 3 months or 5 half-lives ago
Not Eligible

You will not qualify if you...

  • Have serious organ system disorders such as heart, liver, kidney, gastrointestinal, or neurological problems
  • Have had severe psychiatric issues or substance abuse within the past year
  • Have had recent or chronic infections, including tuberculosis or nontuberculous mycobacterium
  • Have other inflammatory diseases like rheumatoid arthritis, lupus, or inflammatory bowel disease
  • Have received live vaccines within the last 8 weeks or Bacillus Calmette-Guerin (BCG) vaccine within the past year
  • Have used glucagon-like peptide-1 (GLP-1) agonists within the last 28 weeks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 52 locations

1

Pa0019 114

Peoria, Arizona, United States, 85381-5025

Actively Recruiting

2

Pa0019 127

Apple Valley, California, United States, 92307

Actively Recruiting

3

Pa0019 111

Covina, California, United States, 91722

Actively Recruiting

4

Pa0019 117

Riverside, California, United States, 92518

Actively Recruiting

5

Pa0019 125

San Leandro, California, United States, 94578

Actively Recruiting

6

Pa0019 126

Temecula, California, United States, 92592

Actively Recruiting

7

Pa0019 141

Upland, California, United States, 91786

Actively Recruiting

8

Pa0019 120

Whittier, California, United States, 90602

Actively Recruiting

9

Pa0019 128

Whittier, California, United States, 90602

Actively Recruiting

10

Pa0019 123

Fort Collins, Colorado, United States, 80528

Actively Recruiting

11

Pa0019 143

Ormond Beach, Florida, United States, 32174

Actively Recruiting

12

Pa0019 113

South Miami, Florida, United States, 33155

Actively Recruiting

13

Pa0019 132

Chicago, Illinois, United States, 60661

Actively Recruiting

14

Pa0019 134

Lansing, Michigan, United States, 48911

Actively Recruiting

15

Pa0019 140

West Long Branch, New Jersey, United States, 07764-1503

Actively Recruiting

16

Pa0019 131

Albuquerque, New Mexico, United States, 87102

Actively Recruiting

17

Pa0019 115

Duncansville, Pennsylvania, United States, 16635

Actively Recruiting

18

Pa0019 142

Rock Hill, South Carolina, United States, 29732

Actively Recruiting

19

Pa0019 116

Jackson, Tennessee, United States, 38305

Actively Recruiting

20

Pa0019 138

Murfreesboro, Tennessee, United States, 37128

Actively Recruiting

21

Pa0019 129

Baytown, Texas, United States, 77521

Actively Recruiting

22

Pa0019 136

Colleyville, Texas, United States, 76034

Actively Recruiting

23

Pa0019 135

Mesquite, Texas, United States, 75150

Actively Recruiting

24

Pa0019 124

Plano, Texas, United States, 75075

Actively Recruiting

25

Pa0019 121

Bellevue, Washington, United States, 98004

Actively Recruiting

26

Pa0019 145

Spokane, Washington, United States, 99216

Actively Recruiting

27

Pa0019 130

Beckley, West Virginia, United States, 25801

Actively Recruiting

28

Pa0019 204

Lovech, Bulgaria

Actively Recruiting

29

Pa0019 205

Pleven, Bulgaria

Actively Recruiting

30

Pa0019 201

Plovdiv, Bulgaria

Actively Recruiting

31

Pa0019 202

Plovdiv, Bulgaria

Actively Recruiting

32

Pa0019 203

Plovdiv, Bulgaria

Actively Recruiting

33

Pa0019 305

Berlin, Germany

Actively Recruiting

34

Pa0019 301

Hamburg, Germany

Actively Recruiting

35

Pa0019 302

Ratingen, Germany

Actively Recruiting

36

Pa0019 306

Wetzlar, Germany

Actively Recruiting

37

Pa0019 407

Bialystok, Poland

Actively Recruiting

38

Pa0019 418

Bialystok, Poland

Actively Recruiting

39

Pa0019 404

Bytom, Poland

Actively Recruiting

40

Pa0019 401

Elblag, Poland

Actively Recruiting

41

Pa0019 412

Krakow, Poland

Actively Recruiting

42

Pa0019 402

Lodz, Poland

Actively Recruiting

43

Pa0019 410

Lublin, Poland

Actively Recruiting

44

Pa0019 413

Nowa Sól, Poland

Actively Recruiting

45

Pa0019 417

Olsztyn, Poland

Actively Recruiting

46

Pa0019 406

Poznan, Poland

Actively Recruiting

47

Pa0019 408

Poznan, Poland

Actively Recruiting

48

Pa0019 411

Poznan, Poland

Actively Recruiting

49

Pa0019 415

Płońsk, Poland

Actively Recruiting

50

Pa0019 414

Warsaw, Poland

Actively Recruiting

51

Pa0019 420

Wroclaw, Poland

Actively Recruiting

52

Pa0019 601

Košice, Slovakia

Actively Recruiting

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Research Team

U

UCB Cares

CONTACT

U

UCB Cares

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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