Actively Recruiting

Age: 18Years +
All Genders
NCT05234463

Study of the Link Between Complement Activation and IgA Nephropathy Severity

Led by University Hospital, Strasbourg, France · Updated on 2025-08-03

400

Participants Needed

1

Research Sites

259 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

ICONE study (IgA Complement and NEphropathy is a prospective monocentric observational study. The main objective is to evaluate the relevance of complement activation as a biomarker of disease severity and progression in patients with a biopsy proven IgAN.

CONDITIONS

Official Title

Study of the Link Between Complement Activation and IgA Nephropathy Severity

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients, male or female, with a biopsy proven IgA nephropathy
  • Includes both primary and secondary forms of IgA nephropathy
  • No restriction on date of diagnosis or level of kidney function
  • Patients with or without history of kidney transplantation
  • Patients followed in the Nephrology Department of Strasbourg University Hospital
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Active or recent infectious or inflammatory syndrome within the last 2 months
  • Recent vaccination within the last 2 months
  • Ongoing treatment for acute humoral rejection
  • Treatment with plasma exchanges within the last 2 months
  • Current treatment with complement inhibitors
  • Inability to provide informed consent due to emergency situations or understanding difficulties
  • Subject under safeguard of justice, guardianship, or curatorship

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Service de néphrologie

Strasbourg, France

Actively Recruiting

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Research Team

S

Sophie Ohlmann- Caillard, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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