Actively Recruiting
A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery
Led by Sir Mortimer B. Davis - Jewish General Hospital · Updated on 2026-03-10
100
Participants Needed
1
Research Sites
148 weeks
Total Duration
On this page
Sponsors
S
Sir Mortimer B. Davis - Jewish General Hospital
Lead Sponsor
M
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborating Sponsor
AI-Summary
What this Trial Is About
A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 100 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).
CONDITIONS
Official Title
A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with persistent erectile dysfunction after prostate surgery, defined as either severe ED (IIEF score 5-7) more than 12 months post-surgery or moderate ED (IIEF score 8-11) more than 18 months post-surgery
- Good erectile function before prostate surgery with baseline IIEF score of 17 or higher on self-report
You will not qualify if you...
- Patients younger than 18 years at diagnosis
- Legally incapable patients
- Patients more than 5 years from prostatectomy
- History of bilateral open inguinal hernia repair
- Pre-existing significant neurological disease
- Diabetes with peripheral nerve involvement and end organ dysfunction
- Coronary artery disease with unstable angina
- Mood disorder with medication changes in past 3 months
- Previous penile base surgery preventing grafting technique, including suprapubic liposuction or suspensory ligament release
- Existing penile prosthesis
- Current use of androgen deprivation therapy
- Use of medications for chronic nerve pain such as gabapentin, amitriptyline, nortriptyline, or pregabalin
- Previous untreated penile trauma
- Medically unfit for surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Jewish General Hospital
Montreal, Quebec, Canada, H3T 1E2
Actively Recruiting
Research Team
V
Victor McPherson, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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