Actively Recruiting
A Study of LY4088044 in Healthy Participants
Led by Eli Lilly and Company · Updated on 2026-05-12
104
Participants Needed
6
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate how well LY4088044 is tolerated and what side effects may occur in healthy participants. The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to check how much LY4088044 gets into the bloodstream and how long it takes the body to eliminate it. The study will last up to approximately 92 weeks for Parts A, B, and C, excluding screening.
CONDITIONS
Official Title
A Study of LY4088044 in Healthy Participants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be overtly healthy based on medical evaluation including history, physical exam, lab tests, vital signs, and cardiac monitoring
- Have a body mass index (BMI) between 18.5 and 30 kg/m²
- Be aged between 18 and 65 years
You will not qualify if you...
- Are individuals assigned female at birth who are pregnant or breastfeeding
- Regularly use drugs of abuse or have positive urine drug screen inconsistent with medication history
- Have hemoglobin levels outside the normal range, iron deficiency, or hemoglobinopathy
- Have an estimated glomerular filtration rate (GFR) less than 90 mL/min/1.73 m²
- Have abnormal 12-lead electrocardiogram (ECG) results
- Smoke more than 10 cigarettes per day or equivalent and cannot follow site smoking rules
- Have weekly alcohol intake exceeding 21 units (males ≤65 years) or 14 units (females and males >65 years) and are unwilling to follow restrictions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Collaborative Neuroscience Network - CNS
Los Alamitos, California, United States, 90720
Not Yet Recruiting
2
ICON
Lenexa, Kansas, United States, 66219
Not Yet Recruiting
3
ICON Early Phase Services
San Antonio, Texas, United States, 78232
Actively Recruiting
4
ICON
Salt Lake City, Utah, United States, 84124
Actively Recruiting
5
New Zealand Clinical Research Christchurch
Christchurch, New Zealand, 8011
Not Yet Recruiting
6
Lilly Centre for Clinical Pharmacology
Singapore, Singapore, 138623
Actively Recruiting
Research Team
T
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
CONTACT
P
Physicians interested in becoming principal investigators please contact
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
6
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