Actively Recruiting
A Study of LY4515100 in Healthy Participants
Led by Eli Lilly and Company · Updated on 2026-03-02
40
Participants Needed
1
Research Sites
23 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main purpose of this study is to assess the safety and tolerability of LY4515100 when given orally to healthy participants. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. The study will last up to 30 days and will include six overnight stays.
CONDITIONS
Official Title
A Study of LY4515100 in Healthy Participants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be overtly healthy as confirmed by medical history, physical exam, lab tests, vital signs, and cardiac monitoring
- Have a body mass index between 18.5 and 32.0 kilograms per square meter (inclusive)
- Be not of childbearing potential
You will not qualify if you...
- Donated 500 milliliters or more of blood in the 30 days before dosing
- Participated in a clinical study with an investigational drug within the last 30 days, or longer if the previous drug has a long half-life
- Have hemoglobin levels outside the normal reference range for age and sex that are clinically significant
- Have an estimated glomerular filtration rate below 90 mL/min/1.73 m2
- Have a 12-lead ECG abnormality that increases risks or may interfere with data analysis
- Used or plan to use medications, including dietary or herbal, within 7 days (or 14 days if enzyme inducer) before dosing
- Smoke more than 10 cigarettes or equivalent daily and cannot follow smoking restrictions at the study site
- Have an average weekly alcohol intake exceeding 14 units (males 65 or younger) or 7 units (females and older males)
- Have evidence of HIV infection, hepatitis B or C infection
- Have liver disease
- Have any medical condition or procedure that may affect drug absorption, distribution, or excretion and interfere with pharmacokinetics assessment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fortrea Clinical Research Unit
Dallas, Texas, United States, 75247
Actively Recruiting
Research Team
T
There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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