Actively Recruiting

Age: 18Years +
All Genders
NCT06243731

A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

Led by Takeda · Updated on 2025-12-16

10

Participants Needed

25

Research Sites

64 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main aim of this study is to assess the safety of maribavir in adults with severe CKD or comorbid ESRD including participants on artificial filtering of the kidney (dialysis) or the blood (hemodialysis). In this study, already existing data will be collected from the participant's medical records. The study will only review data collected as part of the normal clinical routine and will not impact the standard medical care and treatment of participants.

CONDITIONS

Official Title

A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years of age or older at index date
  • Diagnosis of comorbid end-stage renal disease (ESRD) or severe chronic kidney disease (CKD) before index date
  • ESRD confirmed by an estimated glomerular filtration rate (eGFR) less than 15 mL/min/1.73 m²
  • Severe CKD confirmed by an eGFR of 15 to less than 30 mL/min/1.73 m² at index
  • Participant has undergone solid organ transplant (SOT) or hematopoietic stem cell transplantation (HSCT) before index date
  • Participant diagnosed with refractory cytomegalovirus (CMV) infection during the latest post-transplant period
  • Participant started maribavir treatment in routine practice and received at least one dose
  • Informed consent provided where required by local regulations before data collection
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 25 locations

1

Hopital Erasme - PPDS

Anderlecht, Brussels Capital, Belgium, 1070

Not Yet Recruiting

2

UZ Leuven - PPDS

Leuven, Vlaams Brabant, Belgium, 3000

Not Yet Recruiting

3

North Estonia Medical Centre Foundation

Tallinn, Harju, Estonia, 13419

Actively Recruiting

4

Tartu University Hospital

Tartu, Estonia, 60535

Actively Recruiting

5

CHU de Brest - Hopital La Cavale Blanche

Brest, Finistere, France, 29200

Actively Recruiting

6

CHU de Bordeaux - Hopital Pellegrin

Bordeaux, Gironde, France, 33000

Actively Recruiting

7

CHU de Montpellier - Hopital Lapeyronie

Montpellier, Herault, France, 34090

Actively Recruiting

8

CHU de Grenoble Alpes - Hopital Michallon

La Tronche, Isere, France, 38700

Actively Recruiting

9

AP-HP - Hopital Henri Mondor

Créteil, Val-de-Marne, France, 94000

Actively Recruiting

10

Universitatsklinikum Wurzburg

Würzburg, Bavaria, Germany, 97080

Not Yet Recruiting

11

Universitatsklinikum Leipzig

Leipzig, Saxony, Germany, 4103

Not Yet Recruiting

12

Azienda Ospedaliera Dei Colli - Ospedale Monaldi

Naples, Italy, 80131

Not Yet Recruiting

13

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy, 27100

Not Yet Recruiting

14

Hospital Universitario de Bellvitge

L'Hospitalet de Llobregat, Barcelona, Spain, 8907

Not Yet Recruiting

15

Hospital Universitario Cruces

Barakaldo, Vizcaya, Spain, 48903

Not Yet Recruiting

16

Hospital Universitario Vall d'Hebron - PPDS

Barcelona, Spain, 8035

Actively Recruiting

17

Hospital Clinic de Barcelona

Barcelona, Spain, 8036

Not Yet Recruiting

18

C.H. Regional Reina Sofia - PPDS

Córdoba, Spain, 14004

Not Yet Recruiting

19

Hospital Universitario Ramon y Cajal

Madrid, Spain, 28304

Not Yet Recruiting

20

Hospital Regional Universitario de Malaga Hospital General

Málaga, Spain, 29010

Actively Recruiting

21

Hospital Universitario Virgen del Rocio - PPDS

Seville, Spain, 41013

Not Yet Recruiting

22

Dorset County Hospital

Dorchester, Dorset, United Kingdom, DT1 2JY

Not Yet Recruiting

23

Queen Elizabeth Hospital Birmingham

Birmingham, United Kingdom, B15 2GW

Not Yet Recruiting

24

King's College Hospital

London, United Kingdom, SE5 9RS

Not Yet Recruiting

25

Wrexham Maelor Hospital

Wrexham, United Kingdom, LL13 7TD

Not Yet Recruiting

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Research Team

T

Takeda Contact

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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