Measuring Effects of Brain Stimulation on Hand Strength and Function During Awake Brain Surgery for Patients With Tumors in Motor Cortex

What this Trial Is About

Researchers are evaluating a new method to better understand how brain stimulation during awake craniotomies affects hand strength and function in patients with brain tumors invading the primary motor cortex. The study aims to improve the current standard of care, which involves brain surgery with electrical stimulation mapping to avoid permanent neurological damage. Investigators want to develop a standardized way to measure hand movement and explore different stimulation settings to see how they influence motor mapping. Participants will undergo awake craniotomy surgery where additional brain stimulation procedures with varying parameters will be tested beyond the usual care. This will help assess changes in hand strength and movement during the operation. The study focuses on patients with tumors affecting the non-dominant side of the brains motor cortex. The intervention involves direct electrical stimulation applied during surgery to map motor function. During the study, participants will have their hand strength and function quantitatively measured while surgeons apply different stimulation settings. Researchers will monitor how these parameters interrupt or facilitate hand movement. Data collected will include motor strength assessments and functional tests during surgery to better understand brain stimulation effects. The study includes careful monitoring of neurological function throughout the procedure and will track outcomes related to hand movement during the craniotomy.

A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors