Actively Recruiting

Age: 13Years - 35Years
All Genders
Healthy Volunteers
NCT05862389

Study on the Mechanism of Eating Disorder

Led by Peking University · Updated on 2023-05-24

750

Participants Needed

1

Research Sites

430 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Eating disorders (EDs) are severe chronic psychiatric disorders with a not fully understood etiopathogenesis. Previous studies have revealed some biological mechanisms of EDs. However, the etiology and maintenance mechanism of EDs, especially the neuro-mechanisms is still unknown. To explore the pathogenic mechanism and treatment biomarkers of EDs, we design this study. the multidimensional data including the clinicopathological features, neuroimaging data (functional and structural magnetic resonance imaging), electroencephalogram and inflammatory cytokines will be used to investigate the biomarkers for diagnosis and treatment effectiveness.

CONDITIONS

Official Title

Study on the Mechanism of Eating Disorder

Who Can Participate

Age: 13Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of anorexia nervosa according to DSM-5
  • Diagnosis of bulimia nervosa according to DSM-5
  • Age between 13 and 35 years, inclusive
  • Body mass index between 13 and 17.5 kg/m² for anorexia nervosa participants
  • No psychiatric medications taken in the past one month
  • Voluntary informed consent signed by participant or legal guardian if under 18
  • Agreement to participate in all required visits and examinations
Not Eligible

You will not qualify if you...

  • Diagnosis of other major mental disorders including major depressive disorder, anxiety, obsessive-compulsive disorder, personality disorder, intellectual disability, or drug/alcohol dependence
  • Received repetitive Transcranial Magnetic Stimulation (rTMS) or modified electroconvulsive therapy (MECT) within the past six months
  • Severe suicidal tendencies or behaviors
  • Pregnant or breastfeeding women
  • Contraindications for MRI scanning
  • Considered unsuitable for the trial by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Institute of Mental Health, Peking University Sixth Hospital

Beijing, China

Actively Recruiting

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Research Team

T

Tian-Mei Si, Ph.D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Study on the Mechanism of Eating Disorder | DecenTrialz