Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT07131020

Study on the Mechanism of Yifei Moxibustion Improving Immune Function in COPD Based on Plasma Exosome miRNAs

Led by Henan University of Traditional Chinese Medicine · Updated on 2025-08-19

120

Participants Needed

1

Research Sites

68 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study adopted a randomized controlled design, enrolling 90 patients and 30 healthy volunteers. The patients were randomly divided into the Yifei Moxibustion group, the conventional Western medicine treatment group, and the TCM syndrome differentiation treatment group, and were treated for 3 months. Peripheral venous blood was collected from both the healthy volunteers and the patients to observe indicators such as T cell subsets and immunoglobulins, to evaluate the effect of Yifei Moxibustion on improving immune function. The regulation of target genes by exosomes and potential action targets and molecular mechanisms were preliminarily verified through techniques such as nanoparticle tracking technology and flow cytometry.

CONDITIONS

Official Title

Study on the Mechanism of Yifei Moxibustion Improving Immune Function in COPD Based on Plasma Exosome miRNAs

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who meet the diagnostic criteria for stable chronic obstructive pulmonary disease
  • Patients who meet the traditional Chinese medicine diagnostic criteria for lung qi deficiency, lung-spleen qi deficiency, or lung-kidney qi deficiency
  • Aged 18 to 80 years old
  • Voluntarily signed the informed consent form
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Patients with cognitive impairment, confusion, dementia, or mental disorders
  • Patients with unstable angina pectoris or acute myocardial infarction
  • Patients with a history of syncope after exercise or bone and joint diseases affecting exercise
  • Patients with pneumothorax, pleural effusion, pulmonary embolism, or tumors
  • Patients known to be allergic to ingredients of the moxibustion powder

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

the First Affiliated Hospital of Henan University of Chinese Medicine

Zhengzhou, Henan, China, 450056

Actively Recruiting

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Research Team

Y

Yang Xie, Doctor

CONTACT

Y

Yanmin Shi, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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