Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT06992115

A Study of the MIND Diet for Persons With Multiple Sclerosis

Led by Icahn School of Medicine at Mount Sinai · Updated on 2025-10-14

100

Participants Needed

1

Research Sites

207 weeks

Total Duration

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AI-Summary

What this Trial Is About

This study will assess the impact of a MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on brain health and MS symptoms. Participants will be randomly assigned to one of two arms: the diet intervention arm or the "continue current diet"/control arm. Participants randomized to the dietary intervention arm will change their diet to follow a MIND dietary pattern for one year; diet-related education and programming is provided to support this change. Participants randomized to the continue/control arm will be asked to continue their current dietary habits, without major change for one year; multiple sclerosis (MS) MS-related related education and programming (unrelated to diet) is provided. All participants will be asked to provide blood \& stool samples and to complete online questionnaires \& three in-person assessments.

CONDITIONS

Official Title

A Study of the MIND Diet for Persons With Multiple Sclerosis

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18-70 years, inclusive
  • Diagnosed with multiple sclerosis, on any treatment including no treatment
  • MIND diet score of 8 or less at baseline
  • Neurofilament light chain (NfL) parameters determined by age
Not Eligible

You will not qualify if you...

  • Diagnosis of an additional neurodegenerative disease such as Alzheimer's or other serious neurological condition like stroke
  • Current serious medical condition that could affect participation or study results, such as cancer or HIV
  • Pregnancy or planning pregnancy during the study period

AI-Screening

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Trial Site Locations

Total: 1 location

1

Mount Sinai Hospital

New York, New York, United States, 10029

Actively Recruiting

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Research Team

C

Claire E Wigley, Bsc, BSPH

CONTACT

S

Susan Filomena

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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