Actively Recruiting
A Study on the Modulation of Gut Microbiota by Oral Sialic Acid in Healthy Subjects
Led by Xiaolong Li · Updated on 2025-12-10
42
Participants Needed
1
Research Sites
98 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a single-center prospective cohort study conducted by the Department of General Surgery at the Second Affiliated Hospital of Army Medical University (Xinqiao Hospital). The purpose of this study is to explore and clarify the effects of sialic acid intervention on gut microbiota structure, with a focus on the proliferation of pathogens (e.g., Escherichia coli, Klebsiella pneumoniae), and to develop novel prevention and treatment strategies for improving intestinal homeostasis.
CONDITIONS
Official Title
A Study on the Modulation of Gut Microbiota by Oral Sialic Acid in Healthy Subjects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 75 years
- No history of major diseases, no previous surgical history, and no history of cardiometabolic diseases such as hypertension, diabetes mellitus, or obesity
- No use of drugs that may affect gut microbiota or metabolic function, including antibiotics, probiotics, and immunosuppressants
- Voluntarily participate in the study and sign the informed consent form
You will not qualify if you...
- Having other severe diseases such as immunodeficiency, chronic liver disease, renal insufficiency, or malignant tumors
- History of severe infections within the last 3 months or currently receiving anti-infective treatment
- Pregnant women, lactating women, or women planning to become pregnant
- Unable to cooperate with the study protocol or follow-up due to poor compliance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Second Affiliated Hospital of Army Medical University
Chongqing, Chongqing Municipality, China, 400037
Actively Recruiting
Research Team
X
Xiaolong Li, MD
CONTACT
G
Guangsheng DU, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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