Actively Recruiting
A Study of Multiparametric Ultrasound Imaging Methods
Led by Memorial Sloan Kettering Cancer Center · Updated on 2025-12-12
85
Participants Needed
7
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The researchers are doing this study to see how well a type of ultrasound imaging called multiparametric ultrasound (mpUS), can be used to examine, evaluate, and provide information about different cancerous and non-cancerous tissue. The researchers will compare the results of mpUS imaging to standard ultrasound imaging and other standard tests. mpUS imaging is a type of ultrasound imaging that combines different ultrasound methods and analysis to create a more detailed and accurate assessment of tissue. Standard ultrasound provides a basic image of tissue structure, but mpUS imaging can also show blood vessels, blood flow, and detailed tissue structure (microstructure). The researchers think that mpUS may be a better way for evaluating cancer because it combines different ultrasound methods to assess tissue.
CONDITIONS
Official Title
A Study of Multiparametric Ultrasound Imaging Methods
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be at least 50 years old if at high risk for pancreatic cancer or at least 40 if diagnosed with FAMMM syndrome or hereditary pancreatitis
- Be at least 35 years old if diagnosed with Peutz-Jeghers syndrome
- Not pregnant and not nursing
- Relatives at least 21 years old with other high-risk clinical criteria warranting pancreatic cancer surveillance as determined by the project leader
- Agree to be contacted for follow-up
- Meet one of the following pancreatic cancer risk criteria:
- Have two or more affected first-degree relatives in family
- Have at least one affected relative and genetic test confirming a pathogenic variant in specified genes
- Have genetic test confirming pathogenic variants in specified hereditary pancreatitis or cancer genes
- Have other high-risk clinical criteria as determined by the project leader
- Patients with pancreatic ductal adenocarcinoma undergoing endoscopic ultrasound-guided biopsy
- Patients with thyroid nodules undergoing ultrasound-guided thyroid biopsy
- Healthy volunteers aged 18 or older with no known cancer or thyroid nodules and able to give informed consent
You will not qualify if you...
- Unable to sign informed consent for medical or other reasons
- Residents outside the continental United States
- Under 18 years of age
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Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, United States, 11553
Actively Recruiting
Research Team
M
Mark T Burgess, PhD
CONTACT
W
Wyanne Law, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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