Actively Recruiting
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
Led by Hoffmann-La Roche · Updated on 2026-05-07
30
Participants Needed
2
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an investigator- and participant-blind, randomized, placebo-controlled, parallel-group, Phase I study evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of orally administered RO7795081 in otherwise healthy Chinese adult participants with obesity or overweight.
CONDITIONS
Official Title
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy Chinese adults aged 18 to 65 years as confirmed by medical evaluation
- Ethnically Chinese and living in mainland China
- Body mass index (BMI) of 24 kg/m² or higher at screening
- Willingness to follow contraception requirements
You will not qualify if you...
- Any medical condition or disease expected to worsen or change that may bias clinical or mental status assessment or pose special risk
- Clinically significant impairment of endocrine, thyroid, liver, lung, or kidney function
- Unstable or insulin-dependent diabetes mellitus
- Clinically significant cardiovascular disease
- Pheochromocytoma
- History of any psychotic mental illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Nanjing Gulou Hospital
Nanjing, China
Actively Recruiting
2
Ruijin Hospital Shanghai Jiaotong University School of Medicine
Shanghai, China, 200003
Actively Recruiting
Research Team
R
Reference Study ID Number: YP46260 https://forpatients.roche.com/
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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