Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05859191

Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus

Led by University Hospital, Tours · Updated on 2026-04-30

50

Participants Needed

1

Research Sites

362 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Tours

Lead Sponsor

R

Research Center for Respiratory Diseases, Inserm U1100

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study evaluates the variation of expression of the neonatal Fc receptor (FcRn) in Natural Killer T Cells Expressing an Invariant T Receptor (iNKT) and monocytes along with the surface expression of Fc gamma type II receptor (RII) and RIII in active or newly diagnosed lupus patients compared to inactive lupus patients.

CONDITIONS

Official Title

Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age ≥ 18 years
  • Diagnosis of definite systemic lupus which may be associated with secondary antiphospholipid syndrome and/or secondary Gougerot-Sjögren's
  • Lupus patient, newly diagnosed or known, untreated or in relapse
  • Lupus patient considered stable by the treating practitioner
  • Requiring blood sampling for follow-up
Not Eligible

You will not qualify if you...

  • Main autoimmune disease other than lupus
  • Patient under legal protection, guardianship or curators
  • Opposition to data processing

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital

Tours, France, 37044

Actively Recruiting

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Research Team

Y

Yanis RAMDANI

CONTACT

V

Valérie GOUILLEUX-GRUART

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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