Actively Recruiting

Age: 0 - 2Years
All Genders
NCT06681129

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

Led by Boston Children's Hospital · Updated on 2026-03-27

100

Participants Needed

1

Research Sites

510 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Current research on early intestinal development is primarily performed in mouse models. While useful in many other ways, mouse models are not ideal for studying human intestine development as the timing of this process differs between the two species. Further, prior research has demonstrated that some proteins and pathways that are critical in human development have no clear role in mice. This study aims to improve the overall understanding of critical aspects of intestinal development in humans. In addition, this study will investigate the impact of intestinal diseases that are found in the early stages of life such as necrotizing enterocolitis (NEC).

CONDITIONS

Official Title

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

Who Can Participate

Age: 0 - 2Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Neonates or infants up to 2 years old having intestinal surgery or intestinal biopsies from esophogastroduodenoscopy (EGD) or colonoscopy.
Not Eligible

You will not qualify if you...

  • Children older than 2 years.
  • Infants 0-2 years old not undergoing gastrointestinal surgery or intestinal scope with biopsy procedure.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

Loading map...

Research Team

A

Amy O'Connell, MD, PhD

CONTACT

K

Kate Eident, BS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here