Actively Recruiting

All Genders
NCT06850038

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Led by Ipsen · Updated on 2026-04-30

30

Participants Needed

9

Research Sites

236 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will collect information from patients with Alagille syndrome (ALGS) as they use odevixibat (Bylvay) in their daily lives. Odevixibat is a medicine that helps patients with ALGS, a rare disease that harms their liver and causes itching. The main aim of this study is to observe the long-term, everyday effectiveness and safety of the drug odevixibat in patients with ALGS who are receiving ongoing treatment.

CONDITIONS

Official Title

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Alagille syndrome (ALGS)
  • Currently on or starting active treatment with odevixibat
  • Provided signed informed consent and assent as appropriate before any study data collection
Not Eligible

You will not qualify if you...

  • Currently participating in a clinical trial with odevixibat
  • Currently participating in any interventional clinical trial for ALGS
  • Have any contraindication to odevixibat according to the local approved label
  • Had a liver transplant before enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 9 locations

1

Childrens Hospital Los Angeles

Los Angeles, California, United States, 90027

Actively Recruiting

2

UCSF Pediatric Gastroenterology

San Francisco, California, United States, 94158

Actively Recruiting

3

The Children's Mercy Hospital

Kansas City, Missouri, United States, 64108

Actively Recruiting

4

St Louis University. SSM Cardinal Glennon Childrens Medical Center

St Louis, Missouri, United States, 63104

Actively Recruiting

5

Columbia University

New York, New York, United States, 10016

Actively Recruiting

6

NYU Langone - NYU Grossman School of Medicine

New York, New York, United States, 10016

Actively Recruiting

7

Le Bonheur Children's Hospital

Memphis, Tennessee, United States, 38105

Actively Recruiting

8

UT Southwestern Childrens Medical Center

Dallas, Texas, United States, 75235

Actively Recruiting

9

Proactive El Paso,LLC

El Paso, Texas, United States, 79902

Actively Recruiting

Loading map...

Research Team

I

Ipsen Recruitment Enquiries

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment | DecenTrialz