Actively Recruiting
Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
Led by Nantes University Hospital · Updated on 2025-01-16
50
Participants Needed
2
Research Sites
174 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Glaucoma is a chronic disease of the optic nerve, characterized by progressive loss of nerve cells in the retina, leading to progressive loss of peripheral and central vision. There are in fact several types of glaucoma, which is the world's second leading cause of blindness after cataracts, and the leading cause of irreversible blindness. To date, to our knowledge, there is no work analyzing the progression of angiographic OCT in patients with glaucoma. The main aim of this study is to compare the 3-year progression rate of 3 examinations in advanced glaucoma patients: one functional (visual field) and two anatomical (OCTa and OCTrnfl).
CONDITIONS
Official Title
Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women aged 18 and over
- Patient with glaucoma followed in the ophthalmology department of Nantes University Hospital
- Mean visual field deficit (MD) greater than 10 dB
You will not qualify if you...
- Retinal vascular pathologies such as moderate to severe non-proliferative diabetic retinopathy, complicated diabetic retinopathy, retinal vein or artery occlusions
- Non-glaucomatous optic neuropathy or neurological conditions causing visual field deficits
- Retinal panphotocoagulation or retinal cerclage
- Retinal diseases causing visual field impairment like retinitis pigmentosa
- Age-related macular degeneration and other macular diseases causing central vision loss
- Significant eye conditions impairing imaging such as active uveitis or dense cataract
- Loss of fixation point preventing visual field testing
- Pregnant or breastfeeding women
- Adults under guardianship or curatorship
- Unreliable visual fields with false positives or negatives over 33%
- Uninterpretable OCT retinal nerve fiber layer or OCT angiography due to artifacts or low quality
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
CHU Nantes
Nantes, France, 44000
Actively Recruiting
2
Jean-Baptiste Ducloyer
Nantes, France, 44093
Not Yet Recruiting
Research Team
J
Jean-Baptiste Ducloyer, M.D
CONTACT
I
Isabelle Orignac, M.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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