Actively Recruiting
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
Led by Regeneron Pharmaceuticals · Updated on 2026-04-29
120
Participants Needed
3
Research Sites
41 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will test olatorepatide (study drug) to determine how safe and effective this drug is and how easily your body can accept this drug without causing side effects, as well as how the drug is processed in the body by participants with overweight or obesity. The study will test how safe and effective the study drug works compared to placebo in people who are overweight or obese but do not have diabetes. The study is looking at: * What side effects the study drug might cause * How much the study drug is in the blood at different times * How well the study drug works * If the body makes antibodies to the study drug as this may cause the study drug to not work as well
CONDITIONS
Official Title
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Body mass index 27.0 kg/m to <45.0 kg/m at screening
- Willingness and ability to follow the study protocol, including attending visits, following treatment, and completing assessments
You will not qualify if you...
- History of Type 1 or Type 2 diabetes
- Weight change greater than 5 kg within approximately 3 months before screening
- Previous or planned bariatric surgery during the study period
- History of acute or chronic pancreatitis, cholecystitis, symptomatic gallbladder stones
- History of active or untreated malignancy or remission from significant malignancy for less than 5 years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Diablo Clinical Research - Flourish Research
Walnut Creek, California, United States, 94598
Actively Recruiting
2
Clinical Site Partners, LLC DBA Flourish Research
Winter Park, Florida, United States, 32789
Actively Recruiting
3
Flourish Research - San Antonio Medical Trials
San Antonio, Texas, United States, 78229
Actively Recruiting
Research Team
C
Clinical Trials Administrator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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