Actively Recruiting
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-01-23
266
Participants Needed
10
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out how many participants are interested in a surgical preventive procedure after watching an educational video. Before and after watching the video, participants will complete questionnaires in the clinic.
CONDITIONS
Official Title
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 45 years or older
- Scheduled visit with a nongynecologic surgeon
- Female or assigned female at birth
- At least one in situ fallopian tube
- No desire or plan to have children in the future
- Average risk of developing ovarian cancer (no known genetic risk factors)
- Planned nongynecologic, intraabdominal, or pelvic surgery
- Considered suitable candidate by gynecologic and nongynecologic surgeons
- Approved and signed informed consent
You will not qualify if you...
- Not fluent in English or Spanish (except for strong candidates eligible for Part 2 without Part 1)
- Known inherited ovarian cancer susceptibility
- Personal history of gynecologic malignancy
- Carrier of hereditary breast or ovarian cancer gene variants (e.g., BRCA1, BRCA2)
- Suspicious ovarian, fallopian tube, or uterine lesion on preoperative imaging
- Previous bilateral salpingectomy or bilateral salpingo-oophorectomy
- Presence of tubal-implanted birth control devices (e.g., ESSURE) at surgery time
- Current pregnancy
- Emergency procedures requiring consent in inpatient setting or life-threatening situations
- Anticipated significant surgical time increase (>30-40 minutes) due to OS
- Inability to access pelvis during planned procedure
- Known pelvic fibrosis or significant adhesions
- Procedures performed with palliative intent only
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
Johns Hopkins University (Data Collection Only)
Baltimore, Maryland, United States, 21287
Actively Recruiting
2
Dana Farber Cancer Institute (Data Collection Only)
Boston, Massachusetts, United States, 02115
Not Yet Recruiting
3
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
4
Memorial Sloan Kettering Monmouth (Limited protocol activities)
Middletown, New Jersey, United States, 07748
Actively Recruiting
5
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, United States, 07645
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activities)
Commack, New York, United States, 11725
Actively Recruiting
7
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, United States, 10604
Actively Recruiting
8
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
9
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, United States, 11553
Actively Recruiting
10
MD Anderson Cancer Center (Data Collection Only)
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
K
Kara Long Roche, MD
CONTACT
M
Martin Weiser, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
PREVENTION
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here