Actively Recruiting

Age: 18Years - 30Years
All Genders
NCT06891235

Study of Oral Fluid Testing Approach

Led by Boston Children's Hospital · Updated on 2026-03-11

200

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

Sponsors

B

Boston Children's Hospital

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely. The researchers will conduct this fully virtual study among a community sample of 200 individuals aged 18-30 years who have used cannabis at least 1 time per week on average in the past 30 days. Participants will complete oral fluid (saliva) tests, urine tests, and Timeline Follow-back interviews (self-report) that indicate their recent cannabis use (delta-9-THC). Participants will present for 3 virtual study visits across \~3-4 weeks and be asked to complete activities in between: Study Visit 1 (Day 0; informed consent, baseline survey, TLFB interview), Study Visit 2 (\~Day 7; TLFB interview, urine testing), 6 days of at-home videorecorded oral fluid testing, Study Visit 3 (\~Day 21; TLFB interview, urine test, oral fluid test, survey, interview).

CONDITIONS

Official Title

Study of Oral Fluid Testing Approach

Who Can Participate

Age: 18Years - 30Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 30 years
  • Cannabis use at least once per week in the past 30 days
  • Own a smartphone, tablet, or laptop capable of videoconference and videorecording
  • Ability to read and speak English
  • Availability for the full study duration of 3 to 4 weeks
  • Positive urinary THC-COOH test to proceed to oral fluid testing
Not Eligible

You will not qualify if you...

  • Inability or unwillingness to provide contact information

AI-Screening

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Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

L

Lydia A Shrier, MD, MPH

CONTACT

S

Sion K Harris, PhD, RN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Study of Oral Fluid Testing Approach | DecenTrialz