Actively Recruiting
A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With Double Expression Diffuse Large B-cell Lymphoma
Led by Shandong Cancer Hospital and Institute · Updated on 2023-08-15
31
Participants Needed
2
Research Sites
186 weeks
Total Duration
On this page
Sponsors
S
Shandong Cancer Hospital and Institute
Lead Sponsor
T
The First Affiliated Hospital of Nanchang University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a multicenter prospective single arm phase II study, and the purpose of this study is to evaluate the safety and efficacy of orelabrutinib combined with R-CHOP in the treatment of treatment-naïve patients with double expression DLBCL.
CONDITIONS
Official Title
A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With Double Expression Diffuse Large B-cell Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Newly diagnosed double expression diffuse large B-cell lymphoma
- Age between 18 and 70 years
- ECOG performance status between 0 and 2
- Ann Arbor stage II to IV
- Meet clinical trial laboratory testing standards
- Life expectancy of at least 3 months
You will not qualify if you...
- Lymphoma involving the central nervous system
- Uncontrolled cardiovascular or cerebrovascular diseases
- Coagulopathy or connective tissue diseases
- Uncontrolled infections including HBV, HCV, or HIV/AIDS
- Preparing for transplantation
- Pregnancy or active breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
The First Ailliated Hospital of Nanchang University
Nanchang, Jiangxi, China
Actively Recruiting
2
Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Jinan, Shandong, China
Actively Recruiting
Research Team
Z
zengjun Li
CONTACT
D
Dan Liu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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