Study of Blood Factors and Disease Links in Adults With Acute and Chronic Coronary Syndrome Compared to Healthy Controls

What this Trial Is About

Researchers are investigating the changes in various factors such as cell growth factors, inflammatory markers, metabolites, and plasma proteins in the blood of patients with Acute Coronary Syndrome ACS. The study aims to understand how these changes relate to disease prognosis by comparing the ACS group with those having Chronic Coronary Syndrome CCS and a control group without coronary artery or structural heart diseases. Blood samples will be collected within 24 hours of hospital admission to analyze these factors using multi-omics and related research methods. Participants will be categorized into three groups those with ACS, those with CCS, and a control group without heart disease. Blood samples will be taken promptly after hospital admission to measure levels of fibroblast growth factors, inflammatory cytokines, chemokines, cytochrome C, mitochondrial DNA, and malondialdehyde. The study will also examine the relationships between these markers and clinical indicators such as troponin I, brain natriuretic peptide, lactate dehydrogenase, and left ventricular ejection fraction. During the study, participants will undergo peripheral venous blood collection within 24 hours of admission. Researchers will monitor and analyze various blood markers to evaluate their association with heart disease status and prognosis. The studys main outcomes focus on changes in specific circulating factors and their correlation with heart function measures, helping to better understand the biological processes in ACS and CCS. Participation duration depends on hospital admission timing and sample collection.

A Study on the Peripheral Blood in Patients With Acute Coronary Syndrome