Actively Recruiting

Age: 0 - 80Years
All Genders
NCT04847752

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Led by Tongji Hospital · Updated on 2024-06-20

1000

Participants Needed

1

Research Sites

408 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis. From March 1, 2021 to December 31, 2026, 1000 patients with ischemic stroke due to large-artery atherosclerosis who are admitted to the Department of Neurology or Neurosurgery, Tongji Hospital are going to be recruited. Detailed clinical data in emergency room and in-hospital will be obtained from the medical record reviews, and the National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) score will be done by certified neurologists to assess the severity of the disease in acute stage and treatment outcome during the follow-up. All cases will undergo routine blood tests, brain magnetic resonance imaging (MRI) and cerebral vascular examination, such as TCD, CTA, HRMR or DSA. The investigators will analyze the in-hospital factors that could predict the outcome to provide more evidence-based suggestions in the treatment and prognosis of atherosclerotic ischemic cerebrovascular disease.

CONDITIONS

Official Title

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Who Can Participate

Age: 0 - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed ischemic stroke due to large-artery atherosclerosis confirmed by clinical symptoms and imaging
  • Symptomatic superior arch stenosis greater than 50%
  • Asymptomatic superior arch stenosis greater than 70%
  • Provided written informed consent before enrollment
Not Eligible

You will not qualify if you...

  • Brain CT or MRI showing cerebral hemorrhage (including ischemic stroke with hemorrhagic transformation)
  • Severe systemic disease with expected survival less than 3 months
  • Unable to provide continuous follow-up information

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, China, 430030

Actively Recruiting

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Research Team

D

Dai-Shi Tian, Dr.

CONTACT

C

Chuan Qin, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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