Actively Recruiting
A Study on Predictive Models and Clinical Outcome of Radiation Pneumonitis
Led by Huazhong University of Science and Technology · Updated on 2022-10-06
300
Participants Needed
3
Research Sites
287 weeks
Total Duration
On this page
Sponsors
H
Huazhong University of Science and Technology
Lead Sponsor
H
Hubei Cancer Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Radiation pneumonitis is the main dose-limiting toxicity of thoracic radiotherapy, which can affect life quality, survival, and the tumor-controlling effects of patients receiving thoracic radiotherapy. The purpose of this study is to: * Identify biomarkers including serum proteins, gene expression, genetic changes, and epigenetic modifications that determine radiation pneumonitis. * Investigate the relationship between radiation pneumonitis and other toxicities induced by radiotherapy. * Construct a predictive model for radiation pneumonitis. * Evaluate survival and treatment outcome of patients with radiation pneumonitis.
CONDITIONS
Official Title
A Study on Predictive Models and Clinical Outcome of Radiation Pneumonitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of lung cancer by histology
- Radiation dose at least 45 Gy
- Karnofsky score greater than 60
- Age above 18 years
- Life expectancy of at least 6 months
You will not qualify if you...
- Previous thoracic irradiation
- Severe cardiopulmonary diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 43000
Actively Recruiting
2
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
3
Jingjiang People' Hospital
Jingjiang, Jiangsu, China, 214500
Actively Recruiting
Research Team
X
Xianglin Yuan, PhD
CONTACT
L
Lingyan Xiao, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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