Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT05910294

A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-01

50

Participants Needed

7

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are doing this study to look at whether sexual health counselling and using non-hormonal moisturizer at the start of ovarian suppression may be able to prevent or reduce side effects such as vaginal dryness and sexual dysfunction. Researchers will compare how effective this prevention intervention works compared to the usual approach, which is to treat these side effects after they start. All participants will also complete surveys about their sexual health. This information will help researchers learn more about the sexual health of women with breast cancer receiving ovarian suppression.

CONDITIONS

Official Title

A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women 18 years of age or older
  • Breast cancer patients with hormone receptor positive breast cancer, stage 0-III
  • Premenopausal or perimenopausal women who have been pregnant or had at least one menstrual period in the last 24 months or have/had an IUD in place
  • Patients currently on or being started on ovarian suppression
  • Patients without vaginal symptoms of estrogen deprivation and scoring 3 or less on Vaginal and Vulvar Assessment Scales
Not Eligible

You will not qualify if you...

  • Postmenopausal women without periods for 2 or more years
  • Patients scoring 4 or above on Vaginal and Vulvar Assessment Scales
  • Patients already using vaginal atrophy treatments unless stopped for at least 4 weeks

AI-Screening

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Trial Site Locations

Total: 7 locations

1

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

2

Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Middletown, New Jersey, United States, 07748

Actively Recruiting

3

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Montvale, New Jersey, United States, 07645

Actively Recruiting

4

Memorial Sloan Kettering Cancer Center - Suffolk (Limited Protocol Activities)

Commack, New York, United States, 11725

Actively Recruiting

5

Memorial Sloan Kettering Westchester (Limited Protocol Activities)

Harrison, New York, United States, 10604

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

7

Memorial Sloan Kettering Nassau (Limited Protocol Activities)

Uniondale, New York, United States, 11553

Actively Recruiting

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Research Team

S

Shari Goldfarb, MD

CONTACT

J

Jeanne Carter, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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