Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06437067

Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection

Led by Qin Ning · Updated on 2024-05-31

400

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The subjects of this study were inpatients with ACLF who were admitted to Tongji Hospital in Wuhan from March 2023 to June 2025. After patients were enrolled, The patient's general information (gender, age, past medical history, etc.), complications (ascites, hepatic encephalopathy, hepatorenal syndrome, gastrointestinal bleeding, etc.), laboratory tests (CRP, PCT, INR, WBC, fungal/bacterial diagnostic tests, etc.), symptoms and signs at the time of infection, and at admission (D1), D4, D7, D14, D21, etc.) were recorded Save the blood separately. The patients were divided into fungal infection group, bacterial infection group and non-infection group according to the infection status after admission.

CONDITIONS

Official Title

Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Total bilirubin (TBIL) is 12 mg/mL or higher
  • International normalized ratio (INR) is 1.5 or higher
  • Diagnosis of chronic hepatitis B
Not Eligible

You will not qualify if you...

  • Younger than 18 years or older than 80 years
  • Presence of primary hepatic or extrahepatic cancer
  • Severe diseases affecting other organs or systems
  • Pregnancy
  • Incomplete patient information

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Actively Recruiting

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Research Team

T

Tao Chen, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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