Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06174987

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

Led by Daiichi Sankyo · Updated on 2025-10-15

50

Participants Needed

28

Research Sites

210 weeks

Total Duration

On this page

Sponsors

D

Daiichi Sankyo

Lead Sponsor

A

AstraZeneca

Collaborating Sponsor

AI-Summary

What this Trial Is About

This open-label, multicenter, rollover study will provide continued treatment for participants deriving benefit from different therapies received in studies sponsored by Daiichi Sankyo, Inc. (DS) or DS/Astra Zeneca (AZ)-sponsored study (eg. DS8201-A-J101, DS8201-A-U201, DS8201-A-U204, DS8201-A-U207, DS8201-A-U303).

CONDITIONS

Official Title

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent form and willingness to follow all study requirements
  • Currently enrolled in a Daiichi Sankyo or Daiichi Sankyo/AstraZeneca-sponsored parent study that has ended
  • No evidence of disease progression and investigator-assessed clinical benefit from continued treatment with a study drug
Not Eligible

You will not qualify if you...

  • Any unresolved or ongoing adverse events that require stopping the study drug
  • Having been off T-DXd therapy for more than 18 weeks (126 days) between last dose in parent study and start of this study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 28 locations

1

Miami Cancer Institute

Miami, Florida, United States, 33176

Actively Recruiting

2

Duke University - Trent Center

Durham, North Carolina, United States, 27710

Actively Recruiting

3

Flinders Medical Center

Bedford Park, Australia, 5042

Active, Not Recruiting

4

Monash Medical Center

Melbourne, Australia, 3168

Withdrawn

5

Grand Hôpital de Charleroi

Charleroi, Belgium, 6000

Actively Recruiting

6

Instituto Aericas

Rio de Janeiro, Brazil

Not Yet Recruiting

7

A.C. Camargo Cancer Center

São Paulo, Brazil

Not Yet Recruiting

8

IBCC Nucleo de Pequisa e Ensino

São Paulo, Brazil

Not Yet Recruiting

9

Institut Gustave Roussy

Villejuif, France, 94805

Actively Recruiting

10

Rabin Medical Center

Petah Tikva, Israel

Active, Not Recruiting

11

Ospedale San Raffaele

Milan, Italy, 20132

Actively Recruiting

12

Istituto Nazionale Tumori Fondazione G. Pascale

Naples, Italy, 80131

Withdrawn

13

National Cancer Center Hospital

Chūō, Japan, 104-0045

Actively Recruiting

14

Kyungpook National University Chilgok Hospital

Daegu, South Korea, 41404

Actively Recruiting

15

National Cancer Center

Gyeonggi-do, South Korea, 10408

Actively Recruiting

16

Seoul National University Bundang Hospital

Gyeonggi-do, South Korea, 13620

Withdrawn

17

Seoul National University Hospital

Jongno-gu, South Korea, 03080

Actively Recruiting

18

Severance Hospital, Yonsei University

Seoul, South Korea, 03722

Actively Recruiting

19

Asan Medical Center

Seoul, South Korea, 05505

Actively Recruiting

20

Samsung Medical Center

Seoul, South Korea, 06351

Actively Recruiting

21

Complejo Hospitalario Universitario A Coruña

A Coruña, Spain, 15006

Actively Recruiting

22

Hospital Universitari Vall d'Hebron

Barcelona, Spain, 08035

Actively Recruiting

23

Hospital Universitari Dexeus

Distrito de Les Corts, Spain, 08028

Not Yet Recruiting

24

ICO l'Hospitalet - Hospital Duran i Reynals

L'Hospitalet de Llobregat, Spain, 08908

Actively Recruiting

25

Hospital Ruber Internacional

Madrid, Spain, 28034

Withdrawn

26

National Cheng Kung University Hospital

Tainan, Taiwan, 704

Withdrawn

27

National Taiwan University Hospital

Taipei, Taiwan, 10002

Withdrawn

28

Royal Surrey County Hospital

Guildford, United Kingdom, GU2 7XX

Withdrawn

Loading map...

Research Team

D

Daiichi Sankyo Contact for Clinical Trial Information

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here