Quality of Life Study in Boys Ages 6 to 17 Treated for Posterior Urethral Valves in Early Life

What this Trial Is About

Posterior urethral valves PUV are a common congenital blockage in the urethra affecting male children, with significant risks of kidney and urinary problems. About half of those with PUV may develop chronic kidney disease, and some may progress to end-stage renal disease requiring kidney transplantation. Bladder dysfunction and urinary incontinence are common, with varying severity and impact on quality of life, especially in childhood. This observational study focuses on male children aged 6 to 17 years who were treated for PUV in their first year of life at the Femme-Mre-Enfant Hospital in Lyon between 2006 and 2018. The study aims to assess quality of life using the Pediatric Quality of Life Inventory Version 4.0 PedsQL 4.0, capturing aspects such as sleeping, eating, and social functioning, with attention to the impact of urinary and kidney health. Participants will complete the PedsQL 4.0 questionnaire at inclusion to evaluate their quality of life. Researchers will analyze these scores to understand long-term effects of PUV treatment on childrens well-being. The study is sponsored by Hospices Civils de Lyon and is planned to run until August 2028, focusing on how PUV and its treatment affect children during school age.

Study of the Quality of Life in School Aged-children With Posterior Urethral Valves