Actively Recruiting
A Study on Recombinant Botulinum Toxin Type A (YY001) for Injection in Multiple Treatments of Adult Upper Limb Spasticity
Led by Chongqing Claruvis Pharmaceutical Co., Ltd. · Updated on 2026-04-02
300
Participants Needed
16
Research Sites
61 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an open-label, multicenter, phase III clinical study to evaluate the long-term safety and efficacy of multiple treatments with recombinant botulinum toxin type A (YY001) for injection in adult upper limb spasticity
CONDITIONS
Official Title
A Study on Recombinant Botulinum Toxin Type A (YY001) for Injection in Multiple Treatments of Adult Upper Limb Spasticity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years old inclusive at the time of informed consent
- Unilateral hemiplegia caused by stroke with at least 3 months since stroke onset
- Disability Assessment Scale score of 2 or more on the Principal Target of Treatment in hygiene, dressing, limb position, or pain
You will not qualify if you...
- Allergy to any component of the study drug
- Use of any botulinum toxin within 6 months before enrollment or planned use of other botulinum toxins not in the study during the trial
- Fixed contractures in the limb being studied
- Any medical condition increasing risk with botulinum toxin type A use
- Need for drugs that affect neuromuscular function during the study
- Planned or anticipated use of new antispasticity drugs during the study
- History of epilepsy
- Pregnant or breastfeeding women
- Participation in other drug or device clinical trials within 1 month prior to enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 16 locations
1
Peking Union Medical College Hospital
Beijing, China
Actively Recruiting
2
West China Hospital，Sichuan University
Chengdu, China
Actively Recruiting
3
Guangdong Provincial People's Hospital
Guangdong, China
Actively Recruiting
4
Sun Yat-sen Memorial Hospital
Guangzhou, China
Actively Recruiting
5
The Second People's Hospital of Hefei
Hefei, China
Actively Recruiting
6
Huai'an First Hospital Affiliated to Nanjing Medical University
Huai'an, China
Actively Recruiting
7
The First Affiliated Hospital of Henan University
Kaifeng, China
Actively Recruiting
8
The Second Affiliated Hospital of Kunming Medical University
Kunming, China
Actively Recruiting
9
Shanghai Fudan University HuaShan Hospital
Shanghai, China
Actively Recruiting
10
Yangzhi Affiliated Rehabilitation Hospital of Tongji University
Shanghai, China
Actively Recruiting
11
Shenzhen Second People's Hospital
Shenzhen, China
Actively Recruiting
12
The First Affiliated Hospital of Soochow University
Suzhou, China
Actively Recruiting
13
Shanxi Bethune Hospital
Taiyuan, China
Actively Recruiting
14
Tianjin Medical University General Hospital
Tianjin, China
Actively Recruiting
15
Xuzhou Medical University Affiliated Hospital
Xuzhou, China
Actively Recruiting
16
Zibo Municipal Hospital
Zibo, China
Actively Recruiting
Research Team
J
Jieru Bai
CONTACT
X
Xiaoyun Sun
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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