Actively Recruiting
A Study of Revaree Plus in People With Breast Cancer
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-02-06
60
Participants Needed
7
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether Revaree Plus is effective at improving vaginal health for people who are having symptoms of vaginal dryness during breast cancer treatment.
CONDITIONS
Official Title
A Study of Revaree Plus in People With Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older at the time of signing informed consent
- Diagnosis of stage 0 to 3 hormone-receptor positive breast cancer confirmed at MSKCC
- Able to complete study questionnaires in English or Spanish
- Completed primary breast cancer therapy (surgery, chemotherapy, or radiation) or currently on maintenance therapy
- Currently taking an aromatase inhibitor, tamoxifen, or Selective Estrogen Receptor Modulators (SERM)
- No clinical evidence of breast cancer disease at the time of study
- Reporting vaginal symptoms of estrogen deprivation such as vaginal dryness, pain during intercourse, or discomfort during examination
- A score of 4 or greater on the Vaginal Assessment Scale (VAS)
- No history of other cancers except non-melanoma skin cancer
- Willing and able to sign informed consent
You will not qualify if you...
- Unable to provide informed consent
- Vaginal bleeding of unknown cause within 12 months before study entry
- Currently taking local or systemic hormone replacement therapy (must discontinue for 4 weeks before enrollment)
- Using external estrogens or nonhormonal moisturizers (must discontinue for 4 weeks before enrollment)
- Known allergies to any ingredients in the 10mg hyaluronic acid suppository
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Cancer Center Suffolk-Commack (Consent Only)
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10021
Actively Recruiting
7
Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, United States, 11553
Actively Recruiting
Research Team
S
Shari Goldfarb, MD
CONTACT
J
Jeanne Carter, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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