Actively Recruiting
Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery
Led by Maria Cecilia Hospital · Updated on 2024-08-28
300
Participants Needed
1
Research Sites
169 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Coronary artery bypass graft (CABG) surgery is still the standard treatment of coronary revascularization for patients with severe coronary artery disease (CAD). Graft patency, together with completeness of revascularization, is a major determinant of long-term outcome following CABG. The surgical procedure elicits a persistent systemic inflammatory response associated with the activation of the hemostatic system leading to perturbation of endothelial and vascular function and activation of platelets and leukocytes. All of these events are the main players responsible for the early and late graft failure in a significant percentage of patients.
CONDITIONS
Official Title
Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between the ages of 40 and 80
- Ejection fraction greater than 30%
- Have had coronary artery bypass surgery
- Able to give informed consent
- Willing to attend follow-up visits and complete required assessments
You will not qualify if you...
- Emergency intervention
- Changes in liver or kidney function
- Changes in coagulation factors
- Undergoing other interventions such as valve replacement or carotid endarterectomy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MCH
Cotignola, Ravenna, Italy, 48033
Actively Recruiting
Research Team
A
Alberto Albertini, MD
CONTACT
E
Elena Tenti
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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