Actively Recruiting
Study of the Safety, Tolerability, Pharmacokinetics of VV913 Capsules in Chinese Healthy Participants
Led by Vigonvita Life Sciences · Updated on 2026-05-04
56
Participants Needed
1
Research Sites
35 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a randomized, double-blind, placebo-controlled, single ascending-dose study to evaluate the safety, tolerability and pharmacokinetics characteristics of VV913 Capsules in healthy adults.
CONDITIONS
Official Title
Study of the Safety, Tolerability, Pharmacokinetics of VV913 Capsules in Chinese Healthy Participants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male participants aged 18 to 45 years
- Male participants weighing at least 50 kg with a body mass index of 19 to 26 kg/m2
- Normal or clinically insignificant abnormal results in vital signs, physical exam, lab tests, ECG, and chest CT
- Willingness to use appropriate contraception during the study and for 3 months after last dose
- Ability to understand and follow the study protocol and provide signed informed consent
You will not qualify if you...
- Hypersensitivity to VV913 or any of its ingredients
- History of allergies such as asthma, hives, eczema, or drug/food allergies
- Central nervous system, cardiovascular, gastrointestinal, respiratory, urinary, blood, metabolic, or psychiatric disorders requiring treatment or unsuitable for trial
- History of gastrointestinal conditions affecting drug absorption or recent major surgery
- Blood donation or significant blood loss (≥400 mL) or use of blood products within 3 months
- Participation in other clinical trials or use of investigational drugs within 90 days
- Use of prescription, over-the-counter, herbal medicines, or health products within 14 days
- Vaccination within 14 days before screening or planned vaccination during or one week after the study
- History of drug abuse or positive drug screening within 1 year
- Excessive alcohol consumption or smoking exceeding set limits within 1 year
- Inability or unwillingness to quit smoking or drinking during the trial
- Positive tests for hepatitis B, hepatitis C, syphilis, or HIV
- Special dietary requirements or inability to follow a standardized diet
- Inability to avoid foods or drinks affecting drug metabolism during the study
- Intolerance to blood draws or difficulty swallowing capsules
- Female partners planning conception within 3 months
- Any other condition deemed unsuitable by the investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China, 230031
Actively Recruiting
Research Team
H
Huaqing Duan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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